In recent years, High-Intensity Focused Ultrasound and Focused Ultrasound (FUS) have become frequent tools for non-invasive benign tumour therapy. Applications in the treatment of fibroadenoma of uterus has become commercial and passed FDA clearance in 2004 and sonication of bone metastasis has obtained a CE mark. Other tumours are under preclinical (prostate, kidney) and clinical (breast, brain a ...