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 TERMINÉ 
"Synapses of the central nervous system are the cellular structures mediating communication between neurons. Mouse mutations studies of synaptic proteins have shown how they ultimately modulate animal cognition and behavior. Furthermore, there is a growing body of data suggesting a central role of the synapse in neurodegenerative, mental and behavioral disorders. This project aims at understanding ...
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 1

 TERMINÉ 
Europe is facing a rapidly growing threat from Type 2 diabetes mellitus (T2D), which is undoubtedly associated with an unhealthy diet and a more sedentary lifestyle. Evidence is accumulating that gestational diabetes mellitus (GDM) may be playing a role in this process. Thus it provides a significant opportunity for preventing future T2D. Not only is GDM prevalence on the rise, but intrauterine ex ...
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 18

 TERMINÉ 
Objective: To improve the dissemination of evidence-based recommendations by building on the work of the GRADE Working Group to develop and evaluate methods that address the targeted dissemination of guidelines.Background: Healthcare decision makers face challenges in understanding guidelines, including the quality of the evidence upon which recommendations are made, which often is not clear. Gui ...
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 13

 TERMINÉ 

Overcome failure to Publish nEgative fiNdings (OPEN)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2013,

Full information about completed and ongoing clinical trials is the indispensable base for decision making about medical therapies and diagnostic procedures by patients and doctors. Equally, researchers and research organisations, ethics boards, governments and health system agencies, courts for social justice, pharmaceutical companies and all professional groups of the health care system are depe ...
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 11

 TERMINÉ 

Regeneration of Cardiac Tissue Assisted by Bioactive Implants (RECATABI)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2012,

Heart failure is the end-stage of many cardiovascular diseases, but the leading cause is the presence of a large scar due acute to myocardial infarction. Current therapeutic treatments under development consist in cellular cardiomyoplasty where myocardial cells or stem cells are implanted alone or encapsulated in natural scaffolds (collagens) and grafted onto infarcted ventricles with the hope tha ...
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 7

 TERMINÉ 
The main purpose of the EVINCI-study is to test the impact of combined “anatomo-functional” non invasive cardiac imaging for detection and characterization of Ischemic Heart Disease (IHD). The EVINCI-study is a prospective clinical European multicenter trial performed in a cohort of 700 patients with suspected IHD. Patients with intermediate pre-test probability will undergo clinical and biohumora ...
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