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Blood-brain barrier junctions as targets for paracellular drug delivery to the brain (JUSTBRAIN)
Date du début: 1 nov. 2009, Date de fin: 30 avr. 2014,
"To maintain homeostasis of the central nervous system (CNS) the blood-brain barrier (BBB) prevents the free transcellular passage of hydrophilic molecules from the blood into the CNS. Because of this, the BBB is now recognised as the major obstacle to the treatment of most neurological disorders, as it hinders the delivery of many potentially important therapeutic and diagnostic substances to the ...
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