4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research (INTREALL)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,
Though survival of children with acute lymphoblastic leukaemia (ALL) has improved, relapse remains a leading cause of mortality in childhood cancer. Given the rarity of the disease, only a large international cooperative group can recruit sufficient patients for prospective studies with specific questions in biologic subgroups. Under the umbrella of the I-BFM SG all relevant mainly European study ...
Voir le projet
29
Participants partenaires
TERMINÉ
Genome-based biomarkers leading to validated molecular diagnostic tests for response prediction in breast cancer (RESPONSIFY)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2015,
Individualisation of cancer therapy based on standardized biomarker assays is one of the most demanding challenges in cancer medicine. In the RESPONSIFY consortium, we will integrate information on response prediction from different breast cancer types and methodologies into biomarker tests for targeted therapies in the clinical routine setting. Those tests will be developed for commercialisation ...
Voir le projet
14
Participants partenaires
TERMINÉ
Blood-brain barrier junctions as targets for paracellular drug delivery to the brain (JUSTBRAIN)
Date du début: 1 nov. 2009, Date de fin: 30 avr. 2014,
"To maintain homeostasis of the central nervous system (CNS) the blood-brain barrier (BBB) prevents the free transcellular passage of hydrophilic molecules from the blood into the CNS. Because of this, the BBB is now recognised as the major obstacle to the treatment of most neurological disorders, as it hinders the delivery of many potentially important therapeutic and diagnostic substances to the ...
Voir le projet
8
Participants partenaires
TERMINÉ
Identification and validation of new breast cancer biomarkers based on integrated metabolomics (METAcancer)
Date du début: 1 avr. 2008, Date de fin: 31 mars 2011,
Breast cancer is the most common cancer in women. It is therefore in the focus of approaches for the identification of predictive molecular biomarkers. In contrast to transcriptomics, the changes in metabolite levels that are associated with tumor development and progression have not been investigated to a great extent, so far. Metabolomics is defined as the study of all metabolites in a cell, ti ...
Voir le projet