4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Peptide-Drug Conjugates for Targeted Delivery in Tumor Therapy (MAGICBULLET)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,
Many tumor cells are characterized by the overexpression of certain antigens. Molecules that specifically recognize these structures are suitable as homing devices in tumor therapy. Conjugates of anticancer drugs with such a delivery vector targeting tumors would be a “magic bullet” according to the Nobel laureate Paul Ehrlich. Three antibody-drug conjugates (ADC) have already been approved for an ...
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9
Participants partenaires
TERMINÉ
Understanding chronic pain and improving its treatment (EUROPAIN)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2015,
We will establish an international team of leading researchers and clinicians (EuroPain) to undertake multidisciplinary translational research which will: 1) increase the understanding of chronic pain mechanisms; 2)facilitate the development of novel analgesic drugs; and 3) improve the treatment of chronic pain patients.Nineteen researchers drawn from the London Pain Consortium, the Danish Pain Re ...
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29
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TERMINÉ
Small-molecule Inhibitor Leads Versus emerging and neglected RNA viruses (SILVER)
Date du début: 1 oct. 2010, Date de fin: 31 mars 2015,
RNA virus infections kill millions of humans annually, largely due to the lack of suitable vaccines and drugs to control them. This problem is addressed in this FP7 call and in response a consortium of Europe’s and Asia’s leading molecular virologists, structural biologists, medicinal chemists and bioinformaticians has been brought together to generate a state-of-the-art drug discovery and design ...
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25
Participants partenaires
TERMINÉ
European Training Network on (+)RNA Virus Replication and Antiviral Drug Development (EUVIRNA)
Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,
Virus infections remain a major cause of disease, with dramatic costs in mortality, morbidity, and economic loss worldwide. There is an unmet need for potent antiviral drugs, in particular against viruses with a (+)RNA genome which include many important pathogens of humans and animals.Antiviral drug development requires a detailed understanding of virus replication and effective translation of th ...
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