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22 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

European Network for the Study of Adrenal Tumours - Structuring clinical research on adrenal cancers in adults (ENS@T-CANCER)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,

Among patients with adrenal masses Adrenocortical carcinoma (ACC) and malignant pheochromocytomas (MPH) are found with a low incidence but very unfavorable prognosis. Due to this poor clinical outcome, concomitant hormone dysregulation and limited treatment options the two cancer entities severely impact on affected patients. However, the rarity of the tumors also impedes clinical studies which ar ...
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 17

 TERMINÉ 

Solar and Heliospheric Collisionless Kinetics: Enabling Data Analysis of the Sun to Earth Plasma System with Kinetic Modelling (SHOCK)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

This project brings together leading European groups working in the area of kinetic modelling of space plasma to enhance and accelerate the effective scientific exploitation of existing space plasma data sets and to maximize the scientific return of future space missions, both European and international. The fundamental concept of the project is to take advantage in the European context of the syn ...
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 7

 TERMINÉ 

Recruitment and activation of brown adipocytes as preventive and curative therapy for type 2 diabetes (DIABAT)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,

"The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and diabetes due to last years re-discovery of functional BAT in adult humans by several of the members of the ...
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 22

 TERMINÉ 

A Global Approach to Near-Earth Object Impact Threat Mitigation (NEOSHIELD)

Date du début: 1 janv. 2012, Date de fin: 31 mai 2015,

Collisions of asteroids and comets with the Earth have taken place frequently over geological history and have altered the evolutionary course of life; there is no reason why they should not continue to hit the Earth at irregular and unpredictable intervals in the future. Thousands of near-Earth objects (NEOs), mainly asteroids, have been discovered over the past 20 years and the reality of the im ...
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 13

 TERMINÉ 

Gliders for Research, Ocean Observation and Management (GROOM)

Date du début: 1 oct. 2011, Date de fin: 31 déc. 2014,

Underwater gliders are intelligent and affordable platforms, useful for long-term, multi parameter marine observations. Because of their remotely controlled navigational capabilities and the high spatial and temporal resolution of their measurements in real-time, gliders have been identified to fill gaps existing in the existing ocean observing systems. Along with there rapidly growing importance ...
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 21

 TERMINÉ 

Metastatic tumours facilitated by hypoxic tumour micro-environments (METOXIA)

Date du début: 1 févr. 2009, Date de fin: 31 juil. 2014,

"Recent research suggests that the hypoxic micro-environment of tumours is one of the major drivers of metastatic spread of cancer. Furthermore, hypoxic tumour micro-environments may result in treatment resistance of cancer cells, therefore causing a double effect of reducing the potential of a successful treatment of the cancer patient. This project seeks to clarify the roles and functions of the ...
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 21

 TERMINÉ 

Plug and Produce Components for Optimum Dynamic Performance Manufacturing Systems (DYNXPERTS)

Date du début: 1 juil. 2010, Date de fin: 30 juin 2013,

Self-sufficient intelligent plug-and-produce components with advanced sensing and actuating functionalities, e.g. based on smart materials. Able to adapt their range of properties, depending on the changing process conditions. Use vibration for energy harvesting to drive the intelligent system. Smart materials: compensation of static and / or thermally induced dislocations, vibration damping and d ...
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 12

 TERMINÉ 

Quantum Integrated Photonics (QUANTIP)

Date du début: 1 févr. 2010, Date de fin: 30 avr. 2013,

Quantum information science (QIS) is a pioneering field of research at the interface of physics and information science. By harnessing the unique properties of quantum mechanics to encode, transmit and process information, QIS offers significant opportunities to revolutionise information and communication technologies.Of the various physical systems currently investigated, single particles of ligh ...
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 8

 TERMINÉ 

THE REACTIVITY AND TOXICITY OF ENGINEERED NANOPARTICLES: RISKS TO THE ENVIRONMENT AND HUMAN HEALTH (NanoReTox)

Date du début: 1 déc. 2008, Date de fin: 30 nov. 2012,

NanoReTox will identify the potential risks to the environment and human health posed by free engineered (i.e. manmade) nanomaterial by comprehensively addressing five key questions: (1) How does the environment into which nanoparticles are released affect their physicochemical properties and their bioreactivity? (2) How does this impact on their ability to interact with and/or penetrate mammalia ...
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 12

 TERMINÉ 

Effect of ocean Acidification on Marine Invertebrates CALcification in sensitive ecosystems (AMICAL)

Date du début: 1 sept. 2009, Date de fin: 31 oct. 2012,

"Ocean pH has already declined by 0.1 units since pre-industrial times and is predicted to further decline by another 0.3 units by the end of the century as a consequence of increasing anthropogenic CO2. Reef-building corals and calcifying cold-water communities such as pteropods (molluscs), were identified as at higher risk. This project will focus on the effect of rising pCO2 on two sensitive an ...
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 1

 TERMINÉ 

SHaring Interoperable Workflows for large-scale scientific simulations on Available DCIs (SHIWA)

Date du début: 1 juil. 2010, Date de fin: 30 sept. 2012,

Researchers of all disciplines, from Life Sciences and Astronomy to Computational Chemistry, create and use ever-increasing amounts of complex data, and rely more and more on compute-intensive modelling, simulation and analysis. Scientific workflows have become a key paradigm for managing complex tasks and have emerged as a unifying mechanism for handling scientific data. Workflows capture the ess ...
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 7

 TERMINÉ 

Smart Nanostructured Semiconductors for Energy-Saving Light Solutions (SMASH)

Date du début: 1 sept. 2009, Date de fin: 31 août 2012,

Solid state light sources based on compound semiconductors are opening a new era in general lighting and will contribute significantly to a sustainable energy saving. For a successful and broad penetration of LEDs into the general lighting market two key factors are required: high efficiency and low cost. Two new disruptive technologies based on nanostructured semiconductors are proposed to addres ...
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 14

 TERMINÉ 

European Project on Ocean Acidification (EPOCA)

Date du début: 1 mai 2008, Date de fin: 30 avr. 2012,

"The overall goal of the European Project on Ocean Acidification (EPOCA) is to fill the numerousgaps in our understanding of the effects and implications of ocean acidification.EPOCA aims to document the changes in ocean chemistry and biogeography across space and time.Paleo-reconstruction methods will be used on several archives, including foraminifera and deep-seacorals, to determine past variab ...
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 28

 TERMINÉ 

Global Seismic Tomography (GST)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2012,

"This proposal is meant to facilitate the transition of Prof. Auguste (Guust) Nolet from Princeton University back to Europe (Université de Nice/Sophia Antipolis). It addresses three aspects of his current research in global seismic tomography: 1. The merging of seismic data in different frequency ranges, including travel times and amplitudes of phases that do not satisfy the assumptions of geomet ...
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 1

 TERMINÉ 

Molecular, cellular and metabolic neuronal pathways of Fragile X Syndrome (Fragile X pathways)

Date du début: 1 avr. 2009, Date de fin: 31 mars 2012,

Mental retardation (MR) is a major cause of serious handicap, as well as an important medical and social issue, affecting 2-3% of the population. The Fragile X Syndrome (FXS) is the most frequent hereditary cause of MR affecting 1/4000 males and 1/7000 females, due to the inactivation of the X-linked Fragile X Mental Retardation 1 gene (FMR1). In FXS patients and the Fmr1 knock-out mouse, the lack ...
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 1

 TERMINÉ 

Understanding and fighting metastasis by modulating the tumour microenvironment through interference with the protease network (MICROENVIMET)

Date du début: 1 mars 2008, Date de fin: 29 févr. 2012,

"The MICROENVIMET project proposes innovative approaches for building a comprehensive understanding of the interplay between cancer cells and their microenvironment both at primary and secondary sites. The objectives are to identify molecular pathways involved in the regulation of metastatic dissemination to lung, liver, lymph node and bone. To achieve these objectives, the original experimental a ...
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 9

 TERMINÉ 

Seismic Signature of Plumes and the Heat Budget of Earth’s Mantle: Bridging the Gap Between Theoretical High-Performance Computations and Observations (SAPHERE)

Date du début: 1 févr. 2010, Date de fin: 31 janv. 2012,

"The long-lived paradox between geochemical arguments for two compositionally distinct mantle reservoirs and geophysical evidence for extensive mass exchange between upper and lower mantle has still not been resolved in a manner to reach consensus. Recently, finite frequency tomography has produced images of large lower mantle plumes, which potentially carry a significant amount of heat through th ...
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 1

 TERMINÉ 

Managing the complexity of the open source infrastructure (MANCOOSI)

Date du début: 1 févr. 2008, Date de fin: 31 mai 2011,

Description Software is everywhere. And it needs maintenance: upgrades, fixes, new versions... But how can you be sure that a software installation will not break something which was working previously? Did you ever install an upgrade on your PC, just to find out afterwards that something very imp ...
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 10

 TERMINÉ 

Integration and enhancement of key existing European deep-ocean observatories (EuroSITES)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2011,

At present there are a number of fixed point observatories that autonomously measure biological, chemical and physical variables in the oceans around Europe. These operate at various levels of sophistication but in a largely uncoordinated and fragmented manner. There is no agreed set of basic variables and common data protocols are not followed. EuroSITES has two main objectives: 1: To enhance th ...
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 13

 TERMINÉ 

Impact of climate change on light-related carbon fluxes in the Arctic Ocean (Malina)

Date du début: 21 août 2008, Date de fin: 20 déc. 2010,

We currently witness in the Arctic: 1) a decrease in summer ice cover that exposes sea surface to solar radiation and physical forcings, 2) permafrost thawing and increased river runoff, both leading to an increase in the export to ocean of organic carbon previously sequestered in the Tundra, and 3) an increase in ultraviolet radiation. These three phenomena potentially favour a growing mineraliza ...
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 1

 TERMINÉ 

LISA and LISA Path Finder data-analysis (LISA)

Date du début: 1 sept. 2008, Date de fin: 31 août 2010,

"The Laser Interferometer Space Antenna (LISA) mission, due to be launched in ten years' time, will mark a key development in the field of gravitational-wave (GW) physics; whereas ground-based detectors, currently in operation, have a limited sensitivity and will achieve a major result if they can detect individual events, LISA will make GW detection routine and will open the chapter of GW astron ...
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 1

 TERMINÉ 

Mediterranean Coral Calcification in response to global change (MECCA)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2010,

"Global environmental change and the rise of CO2 have been identified as a major threat to scleractinian corals and coral reefs. General predictions are that ocean acidification will be detrimental to reef growth and that 40 to > 80 % of present-day reefs will decline during the next 50 years. While the impact of global change on reef-building corals has been intensely studied, not much is known o ...
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 1