5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Training network for next generation vaccinologists (VACTRAIN)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
Vaccines are the most cost-effective health interventions available (WHO). The impact of vaccination on the health of the world’s population cannot be overstressed. Vaccinolgy is the multidisciplinary discipline of developing vaccine interventions it combines knowledge from basic sciences, medical sciences, public health and social sciences. Ideally a vaccinologists would be able to have a general ...
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9
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TERMINÉ
Biofilm Alliance (BALI)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,
Infections by biofilm-forming microorganisms on indwelling medical devices such as catheters, prosthetic joints and internal fracture fixation devices pose a serious health threat. Overall, approximately 3% of all patients receiving such devices develop biofilm infections, with costs adding up to billions of Euro’s.Current strategies to combat biofilms are based on conventional antibiotics. They o ...
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9
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TERMINÉ
A pharmacogenomic approach to coumarin anticoagulant therapy (EU-PACT)
Date du début: 1 oct. 2008, Date de fin: 31 mars 2013,
"The effectiveness of treatment with oral anticoagulants in the prevention of thrombotic disorders is well established, but these drugs are potentially dangerous because of their narrow therapeutic index. In Europe three coumarins are used: warfarin, acenocoumarol, and phenprocoumon. Genetic factors that have been recently demonstrated to change the pharmacokinetics and pharmacodynamics of coumari ...
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12
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TERMINÉ
"Systems biology of phagosome formation and maturation, modulation by intracellular pathogens" (PHAGOSYS)
Date du début: 1 nov. 2008, Date de fin: 30 avr. 2012,
"To address the question of how intracellular pathogens modulate phagosome trafficking in the host cell we propose to use a systems biology approach, using an iterative cycle of experimental data, model, new experimental data, improved model. The ultimate aim of our project is to develop a mathematical model of mycobacteria and Salmonella infection of macrophages that can be applied to find new in ...
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7
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TERMINÉ
The Physiological Basis of Hypervirulence in Clostridium difficile: a Prerequisite for Effective Infection Control (HYPERDIFF)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2011,
"Clostridium diffficile is currently wreaking havoc within European health systems due to the emergence of hyper virulent strains, responsible for more severe disease, higher relapse rates, increased mortality and greater resistance to antibiotics. Its impact in healthcare settings is considerable, in terms of morbidity, mortality and financial cost However, the physiological basis of pathogenesis ...
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