5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
bioMARkers and molecular tumor classification for non-genotoxic CARcinogenesis (MARCAR)
Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,
MARCAR aims to establish reliable early markers and molecular classification of tumors in non genotoxic carcinogenesis, applying a mechanism-based approach. Benefits are improved drug safety, more efficient drug development, and progress with 3 R issues. MARCAR focuses on rodent liver, the major target organ of non-genotoxic carcinogens (NGC). However, this approach will facilitate predictions for ...
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12
Participants partenaires
TERMINÉ
Paving the way toward HIV eradication/control (Silent HIV)
Date du début: 1 mai 2010, Date de fin: 30 avr. 2015,
Human Immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS, infects primarily cells of the immune system. The outcome of HIV-1 infection results from complex interactions between viral proteins and host cell factors (ref). In most cases, HIV-1 successfully hijacks cellular pathways and bypasses cellular restriction factors for optimal replication leading to continuous rounds of infec ...
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1
Participant partenaire
TERMINÉ
Genotype-To-Phenotype Databases: A Holistic Solution (GEN2PHEN)
Date du début: 1 janv. 2008, Date de fin: 30 juin 2013,
"The GEN2PHEN project aims to unify human and model organism genetic variation databases towards increasingly holistic views into Genotype-To-Phenotype (G2P) data, and to link this system into other biomedical knowledge sources via genome browser functionality. The project will establish the technological building-blocks needed for the evolution of today’s diverse G2P databases into a future seaml ...
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23
Participants partenaires
TERMINÉ
Network of leading MESOcosm facilities to advance the studies of future AQUAtic ecosystems from the Arctic to the Mediterranean (MESOAQUA)
Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,
"In marine ecology there is an urgent need to understand the functioning of the lower part of the pelagic food web, its response to and effect on climate change, its response to pollution and environmental toxins, and its role in producing food for commercially important species at higher trophic level. This requires access for European scientists to tools allowing experimental approaches to near- ...
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6
Participants partenaires
TERMINÉ
Tree Range Evolution under Climate Change (TRECC)
Date du début: 1 févr. 2010, Date de fin: 23 mai 2012,
"Ongoing global warming impacts species' biology, with some species showing population extinction, others displacing their distributional range and/or modify their phenology, either through phenotypic plasticity or genetic modifications. This two-year project aims at evaluating how changing climatic conditions will modify the distributional range of tree species, taking adaptation into account. Mo ...
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