3 projets européens trouvés
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TERMINÉ
Mimicking organs on chips for high throughput drug screening and basic research (MIMIC)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
MIMIC is an interdisciplinary European Industrial Doctorate at the interface of cell biology, engineering and drug development. MIMIC aims to develop and improve novel “organs on chips” technology. This technology combines modern cell biology with microfluidics and chip-based techniques with the goal to mimic organ functionality. There is a high demand by the pharmaceutical industry for more relia ...
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3
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TERMINÉ
STRATEGY TO INHIBIT TGF-Beta IN LIVER DISEASE (IT-LIVER)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
Chronic liver diseases (CLD) and their end-stages, cirrhosis and hepatocellular carcinoma (HCC), are leading causes of morbidity and mortality worldwide with enormous socio-economic costs. Patients with liver cirrhosis are at high risk of deadly hepatic failure and over 80% of HCC develop on a cirrhotic background. HCC ranks as the 5th most common cancer and with >600,000 deaths per annum it const ...
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12
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TERMINÉ
Developing high-thoughput bioassays for human cancers in zebrafish (ZF-CANCER)
Date du début: 1 avr. 2008, Date de fin: 31 mars 2011,
"Recently the zebrafish has emerged as a new important system for cancer research because the zebrafish genome contains all orthologs of human oncogenes and forms tumors with similar histopathological and gene profiling features as human tumors. The zebrafish provides an in vivo vertebrate model for identifying novel mechanisms of cancer progression and for development of new anticancer compounds ...
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