10 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Improving the flow in the pipeline of the next generation of marine biodiscovery scientists (MarPipe)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
MarPipe is a consortium of 11 partners (IBP-CNR, SZN, UiT, UNIABDN, GEOMAR, KULeuven, UCC, eCOAST, MEDINA, MicroDish, Italbiotec) based in 8 countries (I, N, UK, D, B, IRL, E, NL), including 3 from the non-academic sector. We will train 11 ESRs in marine drug-discovery, providing these researchers with unique skills toward becoming world leaders in this research field and to advance their careers ...
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11
Participants partenaires
TERMINÉ
European Gram Negative Antibacterial Engine (ENABLE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,
The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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42
Participants partenaires
TERMINÉ
Ocean Medicines
Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,
Marine organisms have the capacity to produce a variety of biologically potent natural products. Such novel molecules have new mechanisms of action and therefore could be used to treat human diseases and enhance the quality of life, especially in the ageing segment of the population. However, although there is growing interest in marine natural products (MNP) as potential therapeutic agents for hu ...
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9
Participants partenaires
TERMINÉ
Boosting scientific excellence and innovation capacity in biorefineries based on marine resources (BLUEandGREEN)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,
...p with four internationally-leading counterparts at the EU level: the University of Helsinki, Finland, the University of Bergen, Norway, GEOMAR, Helmholtz Centre for Ocean Research Kiel, Germany, and Fundación MEDINA, Spain. BLUEandGREEN scientific strategy includes: to review the latest research and innovation advances in the sector, identify and address institutional network gaps and deficienci ...
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5
Participants partenaires
TERMINÉ
Exploitation of microbial biodiversity for the discovery and development of novel cosmeceutical agents (MICROSMETICS)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,
"MICROSMETICS aims to discover and carry to the stage of development innovative products in the area of cosmeceuticals originating from global biodiversity using emerging and state of the art technologies in the field of biotechnology, natural products chemistry and applied microbiology. These objectives will be implemented through an extended and balanced scheme of researcher’s exchanges and recr ...
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8
Participants partenaires
TERMINÉ
Increasing Value and Flow in the Marine Biodiscovery Pipeline (PHARMASEA)
Date du début: 1 oct. 2012, Date de fin: 31 mars 2017,
The PharmaSea project focuses on obstacles in marine biodiscovery research, development and commercialization and brings together a broad interdisciplinary team of academic and industry researchers and specialists to address and overcome these. The partners are ideally placed to demonstrate how to widen the bottlenecks and increase the flow of ideas and products derived from the marine microbiome ...
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25
Participants partenaires
TERMINÉ
Thoroughly Optimised Production Chassis for Advanced Pharmaceutical Ingredients (TOPCAPI)
Date de fin: 1 janv. 2017,
TOPCAPI will exploit the natural fabrication power of actinomycetes as microbial cell factories to produce three high value compounds: GE2270, a starter compound for the semi-synthesis of NAI-Acne, a new topical anti-acne drug in Phase II clinical trials; 6-desmethyl-tetracycline (6DM-TC) and 6-desmethyl 6-deshydro tetracycline (6DM6DH-TC), intermediates for semi-synthetic conversion to medically ...
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8
Participants partenaires
TERMINÉ
A systematic analysis of parasite metabolism - from metabolism to intervention (ParaMet)
Date du début: 1 juin 2012, Date de fin: 31 mai 2016,
Parasites exact a devastating toll on health and economic productivity, infecting man and also domestic livestock. Drugs used to combat parasitic diseases are deficient in many ways and new, better drugs are needed to establish sustainable means to combat diseases caused by protozoan parasites that include malaria, trypanosomiasis and leishmaniasis in man, and coccidiosis among others in animals. ...
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12
Participants partenaires
TERMINÉ
Novel applications of diffusion NMR spectroscopy in microbial natural products research (DOSYMNPS)
Date du début: 1 sept. 2011, Date de fin: 31 août 2015,
Natural products have inspired chemists by their rich structural diversity and complexity while playing a pivotal role as sources for drug lead compounds during the last century. However, in order for natural products chemistry to continue to be competitive with purely synthetic based drug discovery methods, there is a need to continually improve the efficiency of the source selection, screening, ...
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1
Participant partenaire
TERMINÉ
Cocultivation of microorganisms as a strategy for discovery of new natural products with antimicrobial properties (CoculMicro)
Date du début: 1 août 2011, Date de fin: 31 juil. 2015,
New antibiotics are urgently needed to combat persistent, emerging and re-emerging infectious diseases. Historically, microbial natural products have been a prolific source of antibacterials, and the screening of microbial extracts has yielded many classes of antibiotics. However, this approach was largely abandoned by big pharma because of the high rates of rediscovery of known antibiotics, and t ...
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