Rechercher des projets européens

Parasites exact a devastating toll on health and economic productivity, infecting man and also domestic livestock. Drugs used to combat parasitic diseases are deficient in many ways and new, better drugs are needed to establish sustainable means to combat diseases caused by protozoan parasites that include malaria, trypanosomiasis and leishmaniasis in man, and coccidiosis among others in animals. ...

"The aim of this project is to design and synthesize helically folded aromatic oligoamides that chemically and structurally mimic the surface of double stranded DNA. The potency of these foldamers to interact with DNA processing enzymes relevant in cancer therapy will be assessed in order to establish structure-activity relationships. The research program primarily involves the chemical synthesis ...