4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Ultra-low dose of IL-2 for the treatment of recently diagnosed type 1 diabetes (DIABIL-2)
Date du début: 1 oct. 2012, Date de fin: 31 mars 2019,
ConceptThe discovery of regulatory T cells (Tregs) has revolutionized our understanding of autoimmune diseases. As T1D is caused by the failure of Tregs to block autoimmune destruction of pancreatic ß-cells, Treg stimulation has the potential to stop the process, preserve ß-cells’ insulin secretion, and likewise prevent or delay disease progression and improve clinical outcome for patients.Backgro ...
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7
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TERMINÉ
Clinical safety, immunogenicity and efficacy of a therapeutic vaccine that combines peptides mimicking antigen receptors on autoimmune B and T cells associated with myasthenia gravis (Myasterix)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
The MYASTERIX project will advance a therapeutic vaccine candidate (designated orphan drug) indicated for the autoimmune disease myasthenia gravis (MG) to clinical proof of concept studies. MG is caused by T cell dependent antibodies that bind to and deplete acetylcholine receptors (AChR) at neuromuscular junctions causing muscle weakness by interfering with neuromuscular transmission and junction ...
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6
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TERMINÉ
European Research Infrastructure on Highly Pathogenic Agents (ERINHA)
Date du début: 1 nov. 2010, Date de fin: 31 août 2014,
In the context of the emerging and re-emerging infectious diseases involving highly pathogenic microorganisms, European countries have to be well-prepared to face such threats. However, the Biosafety Level 4 (BSL4) capacity in Europe is not sufficient enough to cover the efficient development of diagnosis, prophylactic and therapeutics means against these pathogens. Moreover, there is no global co ...
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27
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TERMINÉ
European Framework for Measuring Progress (e-Frame)
Date du début: 1 janv. 2012, Date de fin: 30 juin 2014,
Within the framework of the Work Programme 2011 on Socio-economic Science and Humanities e-Frame project builds on the latest political directions of the European Commission, in particular the priorities identified in the Europe 2020 strategy. The project will focus on the following general objectives: stocktaking of available results and of ongoing research activities on progress measurement; fos ...
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