6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
3-O-sulfated heparan sulfate translocation in altered membrane biology: A newstrategy for early population screening and halting Alzheimer’s neurodegeneration (ArrestAD)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
ArrestAD proposes a novel and visionary thinking resulting from the demonstration of the central role of a particular heparan sulfate species at the intracellular level in neurons and in circulating cells in the molecular pathology of Alzheimer’s disease (AD). AD is a societal challenge for which there is neither prevention nor possible cure. Research in the field has long been refining classic co ...
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8
Participants partenaires
TERMINÉ
European Clinical trials in Rare Sarcomas within an integrated translational trial network (EUROSARC)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2016,
Sarcomas are rare malignant tumors, with an overall incidence of 6/105/year. Bone and soft tissue connective tissue tumours encompass more than 50 different rare histotypes and more than 150 different molecular subtypes. The incidence of individual rare sarcomas subtypes is often less than 0.5/105/year. Given sarcoma rarity as a group, but even more as individual entities, few prospective clinical ...
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22
Participants partenaires
TERMINÉ
Next Generation Sequencing platform for targeted Personalized Therapy of Leukemia (NGS-PTL)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2015,
"Hematological diseases are highly heterogeneous malignancies in the matter of the molecular mechanisms related to their development and progression. A considerable heterogeneity can be further observed within the same hematological disease at the inter-individual level, being reflected by different clinical outcomes and responses to treatment in different patients. Nowadays, the advent of high-th ...
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10
Participants partenaires
TERMINÉ
Proteomics Standards International Molecular Exchange - Systematic Capture of Published Molecular Interaction Data (PSIMEx)
Date du début: 1 mars 2009, Date de fin: 31 août 2013,
The aim of the PSIMEx proposal is to systematically make published molecular interaction data computationally accessible. We plan to further develop the existing standard for molecular interactions developed by the HUPO Proteomics Standards Initiative, and to promote its implementation in the entire chain from experiment planning via data formatting and analysis to data representation in journal p ...
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15
Participants partenaires
TERMINÉ
Biobanking and Biomolecular Resources Research Infrastructure (BBMRI)
Date du début: 1 févr. 2008, Date de fin: 31 janv. 2011,
The Preparatory Phase for a pan-European Biobanking and Biomolecular Resources Research Infrastructure (BBMRI) will focus on technical, legal, governance, and financial issues to • prepare to construct BBMRI, building on existing biobanks, resources and technologies, specifically complemented with innovative components and properly embedded into European scientific, ethical, legal and societal fra ...
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55
Participants partenaires
TERMINÉ
Understanding and fighting metastasis via dissection of the Core Invasive Machinery (MetaFight)
Date du début: 1 janv. 2008, Date de fin: 31 déc. 2010,
The co-operative Metafight project will perform functional studies to understand the dissemination and outgrowth of metastasis through systematic analysis of the Core Invasive Machinery contained within integrin-mediated ECM attachment structure. It includes a large and discretely localised intracellular signalling network which drives migration and invasion. Our strategy is based on the hypothesi ...
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