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17 projets européens trouvés

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 TERMINÉ 

AnTBiotic – progressing TB drug candidates to clinical proof of concept (anTBiotic)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Tuberculosis (TB) today rivals HIV/AIDS as the leading cause of death from infectious diseases. The number of TB patients has never been higher and the growing proportion of drug-resistant TB is threatening control strategies both in the developing and developed world, Eastern Europe being a particularly worrying point in case. The anTBiotic consortium aims to fuel the long-term TB clinical pipeli ...
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 5

 TERMINÉ 

Nanotherapeutics for antibiotic resistant emerging bacterial pathogens (NAREB)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Increase in antibiotic resistance is a global concern worldwide. The project NAREB's main objective is the optimization of several nanoformulations of antibacterial therapeutics in order to improve the therapy of multi-drug resistant (MDR) tuberculosis (TB) and MRSA infections in European MDR patients.NAREB will address the problem of drug bioavailability inside the infected macrophages, transport ...
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 16

 TERMINÉ 

Auszubildende Biologielaboranten arbeiten in europäischen Labors

Date du début: 1 juin 2016, Date de fin: 31 mai 2017,

Nine trainees to become biological assistants and one trainer from the Research Center Borstel would like to attend the program. The trainees will spend a four week stay in a laboratory for microbiology in Lisbon or Zagreb, a laboratory of biochemistryl and molecular biology in Madrid or a laboratory for veterinary medicine in Palermo (Sicily). At the time of their stay all trainees have started t ...
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 5

 TERMINÉ 

Next Generation Genome Based High Resolution Tracing of Pathogens (PathoNgen-Trace)

Date du début: 1 janv. 2012, Date de fin: 30 juin 2016,

"Next generation sequencing (NGS) has fundamentally altered genomic research. New developments will bring NGS costs and performance down to an everybody's technology with extreme potential for ultra fast and accurate molecular typing and diagnostic as it provides the ultimate whole genome information. However, technical and bioinformatics constraints, restrict the application of NGS to few highly ...
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 8

 TERMINÉ 

Auszubildende Biologielaboranten lernen in Europa

Date du début: 1 juin 2015, Date de fin: 31 mai 2016,

Fourteen trainees to become biological assistants worked in small groups for 4 weeks in Sweden, Portugal, Denmark or Italy. The duties of the trainees were to attend practical works in the lab and to get an overview of the theoretical background of the topics. All trainees were full age and in the third year of apprenticeship. The working areas and the methods performed in the foreign groups were ...
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 5

 TERMINÉ 

Auszubildende Biologielaboranten erforschen Europa

Date du début: 1 juil. 2014, Date de fin: 30 juin 2015,

Eight trainees to become biological assistants and one member of the teaching staff from the Research Center Borstel would like to attend the program. They will spend a four week stay in a laboratory for microbiology in Lisbon or in a laboratory for veterinary medicine in Palermo (Sicily). At the time of their stay all trainees have started their third year of training. Their qualifications in the ...
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 2

 TERMINÉ 

Biology and control of vector-borne infections in Europe (EDENext)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,

To address the call for proposals 'Biology and control of vector-borne infections in Europe' launched by the European Commission, we want to investigate the biological, ecological and epidemiological components of vector-borne diseases (VBD) introduction, emergence and spread, and to propose innovative tools for controlling them, building on the basis of acquired knowledge. We have selected the ma ...
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 54

 TERMINÉ 
The proposal deals with the establishment of control measures for two major tick-borne diseases of small ruminants: theileriosis caused by Theileria lestoquardi and T. uilenbergi and babesiosis caused by Babesia ovis. The research programme aims at improving existing and producing new attenuated vaccines, designing subunit vaccines and capability building. To achieve these goals the proposal will ...
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 15

 TERMINÉ 
The aim of this project is to develop a new generation vaccine for schistosomiasis. The vaccine will be based on exposed proteins and/or glycans of the vulnerable skin stage schistosomula, making it safe and effective. The life stage-specific vaccine target selection strategy is based on state-of-the-art schistosomal transcriptomics and glycomics technologies and data, and unique serum and sample ...
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 14

 TERMINÉ 
"This proposal will establish an integrated and synergistic network to address the challenge of multiple drug resistant tuberculosis (MDR-TB) facing the EU. The objective will be attained through the establishment of a European consortium of expert partners with extensive experience in the conduct of basic and clinical research relating to MDR-TB, TB control and epidemiology. This Consortium will ...
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 32

 TERMINÉ 
"In the context of global warming and globalisation, tick and tick-borne diseases (TTBD) are expected to emerge, with an increasing risk for animals and humans. It is imperative therefore to build up training capacities to improve integrated control measures, including the development of efficient and appropriate vaccines. The POSTICK ITN aims to (1) design new effective control strategies for TTB ...
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 9

 TERMINÉ 
Epidemiological and experimental evidence supports a link between chronic inflammation and cancer and indicates a role for inflammatory cells in the initiation, progression and metastasis of malignancy. The objective of the collaborative integrated project INFLA-CARE is to structure a European collective of scientific and technological excellence in the field of ‘Inflammation & Cancer’ which will ...
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 22

 TERMINÉ 
Tuberculosis (TB) accounts amongst the most deadly infectious diseases worldwide. Despite the availability of a vaccine and effective drugs, Mycobacterium tuberculosis, the etiologic agent of TB, still defies the humanity. An alarming increase in drug resistance and emergence of outbreaks has made it urgent the need for increased surveillance and control. With its structured global geographical di ...
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 7

 TERMINÉ 
"West Nile Fever (WNF), Rift Valley Fever (RVF) and Crimean-Congo Haemorrhagic Fever (CCHF) are arthropod-borne diseases of different domestic and wild animals and can also affect humans, posing a great threat to public health because of their epidemic and zoonotic potential. Their geographical distribution has expanded in recent decades. WNF outbreaks have already occurred in Europe, CCHF is ende ...
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 26

 TERMINÉ 

The role of membrane trafficking in immune cell function (Membrane Dynamics)

Date du début: 3 sept. 2007, Date de fin: 2 sept. 2011,

Recently, receptor signal transduction has been identified to occur not only at the plasma membrane, but also at various intracellular compartments. Hence, receptor trafficking and signal compartmentalization may contribute to a higher level of cellular organization. The proposal’s objective is to understand fundamental principals in the regulation and biology of membrane trafficking and signal co ...
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 1

 TERMINÉ 
"Recent developments in molecular tools combined with updated epidemiological data provide novel challenges to the development of modern molecular diagnostics. The increasing threat of infections due to Mycobacterium tuberculosis, including multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections poses important questions that call for development of integrated tools for rapid dia ...
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 9

 TERMINÉ 
Haemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening inherited immune disorder of early childhood characterised by an uncontrolled immune response. Three disease causing genes have been identified in about half of the patients. Diagnosis is difficult, pathophysiology poorly understood, and treatment unsatisfactory with about 40% of the children dying from treatment failure or t ...
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 9