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Dual targeting of senescence and tumor immunity for cancer therapy (Immune-senescence)
Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,
We have previously demonstrated that cellular senescence opposes tumorigenesis thereby opening up new potential opportunities for cancer treatment. Senescence and tumor immunity in cancer are tightly interconnected. Tumor-infiltrating immune cells promote the clearance of senescent tumor cells thereby contributing to the tumor suppressive function of senescence. Moreover, T lymphocytes can drive s ...
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