5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
New experimental therapeutic approaches for Parkinson’s disease by direct DA neuronal reprogramming (REPROPARK)
Date du début: 1 juin 2014, Date de fin: 31 mai 2019,
Neurodegenerative diseases cause a significant burden on the elderly population in Europe. Parkinson’s disease (PD) affects 1.2 million people in Europe and with the increasing life expectancy this number will rise, putting more pressure on health care. Treatment of PD is only symptomatic, and therefore, there is an urgent need for more efficient therapies. Degeneration of mesencephalic DA neurons ...
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2
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TERMINÉ
The MEtabolic Road to DIAstolic Heart Failure (MEDIA)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,
More than 50% of heart failure (HF) patients present without a major deficit of left ventricular (LV) systolic function and are presumed to suffer from diastolic HF (DHF) because diastolic LV distensibility is usually impaired in these patients. The vast majority (~80%) of DHF patients is exposed to metabolic risk factors. The MEDIA consortium therefore investigates:1) how metabolic derangements c ...
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23
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TERMINÉ
"Early detection of HIV-1 using ultra-sensitive, rapid capacitive biosensor" (CAPHIV)
Date du début: 1 sept. 2011, Date de fin: 30 sept. 2013,
"The HIV pandemic continues to be a worldwide public-health problem. The virus, which is spread through sexual contact, exposure to infected blood, or through shared syringes, is highly infective, rapidly mutates, and has no cure. Because there is no effective vaccine or other prophylaxis available, the current best practice and standard of care for those infected is an early, accurate diagnosis ...
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7
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TERMINÉ
Restorative Plasticity At Corticostriatal Excitatory Synapses (REPLACES)
Date du début: 1 nov. 2008, Date de fin: 30 avr. 2013,
"Long-lasting, activity-dependent synaptic changes are thought to underlie the ability of the brain to translate experiences into memories and seem to represent the cellular model underlying learning and memory processes. Alteration of brain plasticity may lead to the motor and cognitive disturbances observed in neurodegenerative diseases. Therapeutic approaches targeting synaptic plasticity could ...
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12
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TERMINÉ
European Network for Cell Imaging and Tracking Expertise (ENCITE)
Date du début: 1 juin 2008, Date de fin: 30 nov. 2012,
"Cell therapy can be defined as the transplantation of living cells for the treatment of medical disorders. Three different principles underlie the increasing interest in cell therapy. 1. Transplanted cells used as an “active drug” 2. Transplanted cells used to replace damaged and degenerated tissue. 3. Cells used as a drug delivery vehicle. Promising results have been obtained in pre-clinical and ...
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