7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Regulation of inflammasome activity through NLRP3 ubiquitination level (UbInflam)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,
The innate immunity constitutes an efficient barrier by rapidly detecting pathogens and tissue damages through pattern recognition receptors including NLRP3. On the other hand, inappropriate NLRP3 activation causes deleterious inflammation and contributes to various conditions including atherosclerosis, diabetes, gout and Alzheimer's diseases. Therefore NLRP3 requires tight regulation that remains ...
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1
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TERMINÉ
The Human Early-Life Exposome – novel tools for integrating early-life environmental exposures and child health across Europe (HELIX)
Date du début: 1 janv. 2013, Date de fin: 30 juin 2017,
The aim of HELIX is to exploit novel tools and methods (remote sensing/GIS-based spatial methods, omics-based approaches, biomarkers of exposure, exposure devices and models, statistical tools for combined exposures, novel study designs, and burden of disease methodologies), to characterise early-life exposure to a wide range of environmental hazards, and integrate and link these with data on majo ...
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16
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TERMINÉ
What You Say Is What You Did (WYSIWYD)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,
The What You Say Is What You Did project (WYSIWYD) will create a new transparency in human robot interaction (HRI) by allowing robots to both understand their own actions and those of humans, and to interpret and communicate these in human compatible intentional terms expressed as a language-like communication channel we call WYSIWYD Robotese (WR). WYSIWYD will advance this critical communication ...
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7
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TERMINÉ
AUTOPHAGY AND VIRULENCE OF HEPATITIS C VIRUS (HepATG)
Date du début: 1 août 2012, Date de fin: 31 juil. 2016,
Autophagy is a major intracellular pathway for cellular homeostasis. It also plays an essential role in antiviral response against diverse pathogens. Indeed, in addition to the removal of viral protein aggregates from the cells, autophagy is emerging as a key regulator of viral propagation by regulating positively or negatively the secretion of interferon α/β (IFNα/β) and inflammatory molecules, k ...
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1
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TERMINÉ
Reproductive Biology Early Research Training (REPRO-TRAIN)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
The “Reproductive Biology Early Research Training” network (REPRO-TRAIN) aims to provide all the elements required to train the nextgeneration of researchers with the latest skills to solve the current societal problems in male reproductive biology (Andrology). Thedecline in sperm counts and concomitant increase in testicular cancer demands research in this field as an urgent priority.Spermatogene ...
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8
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TERMINÉ
New Algorithms for Host Pathogen Systems Biology (SYSPATHO)
Date du début: 1 oct. 2010, Date de fin: 31 mars 2015,
SYSPATHO focuses on the development of novel and generally applicable mathematical methods and algorithms for systems biology. These methods and algorithms will be applied to study the complex interactions of hepatitis C virus (HCV), a human-pathogenic virus of high medical relevance, with its host at the systems level. Using a multidisciplinary, integrative approach, PATHOSYS will (a) develop met ...
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11
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TERMINÉ
Role of microRNAs in host responses to Crohn's disease-associated adherent-invasive Escherichia coli (MiRNA-AIEC)
Date du début: 1 août 2012, Date de fin: 31 juil. 2014,
Recent studies have shown dysregulation of microRNAs (miRNAs) in the mucosa of Crohn’s disease (CD) patients, suggesting a role for miRNAs as contributors to inflammatory bowel disease (IBD) susceptibility. The scientists from the host institution previously showed that ileal lesions in CD patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC), which are able to invade and ...
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