5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
DIabetes REsearCh on patient sTratification (DIRECT)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2019,
The overarching aims of the DIRECT consortium, consisting of 20 leading academic groups in diabetes and 5 EFPIA companies, are to identify biomarkers that address current bottlenecks in diabetes drug development and to develop a stratified medicines approach to treatment of type 2 diabetes with either existing or novel therapies.There is heterogeneity in who develops diabetes, the rate at which th ...
Voir le projet
27
Participants partenaires
TERMINÉ
Stem cells for Biological Assays of Novel drugs and prediCtive toxiCology (StemBANCC) (STEMBANCC)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
StemBANCC, comprising internationally renowned investigators, is ideally positioned to deliver a unique European biorepository and drug discovery pipeline based upon human induced pluripotent stem cells (hiPSC). This unrivalled opportunity will address the pressing therapeutic need in neurodegeneration, neurodysfunction and diabetes. We have immediate access to richly phenotyped subjects with a we ...
Voir le projet
38
Participants partenaires
TERMINÉ
Systems Biology of Colorectal Cancer (SYSCOL)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
Colorectal cancer (CRC) is one of the most common cancers in both males and females, and it is perhaps the best understood of all epithelial tumors in terms of its molecular origin. Yet, despite large amount of work that has concentrated on understanding of colon tumorigenesis, we still do not know the full complement of molecular lesions that are individually necessary – and together sufficient – ...
Voir le projet
11
Participants partenaires
TERMINÉ
Identifying biomarkers of ageing using whole transcriptomic sequencing (EuroBATS)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2014,
Ageing is a fundamental biological process that defines all aspects of life, yet the understanding of the basic biological interactions leading to ageing and how genetic and environmental variation contributes to this processes are still largely unknown. We propose to use the most up to date genomic and epidemiological methodologies to shed light in some of the key questions in ageing research. We ...
Voir le projet
5
Participants partenaires
TERMINÉ
Sharing capacity across Europe in high-throughput sequencing technology to explore genetic variation in health and disease (GEUVADIS)
Date du début: 1 oct. 2010, Date de fin: 31 déc. 2013,
"High-throughput next-generation DNA sequencing technologies allow investigators to sequence entire human genomes at an affordable price and within a short time frame. The correct interpretation, storage, and dissemination of the large amount of produced genomics data generate major challenges. Tackling these challenges requires extensive exchange of data, information and knowledge between medical ...
Voir le projet