7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Adverse Immune Signatures and their Prevention in Corneal Transplantation (VISICORT)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,
"Immune system response is the most complex barrier to long-term success of tissue transplants/implants from allogeneic and bio-artificial sources. While newly developed tissue transplant procedures are not yet performed frequently enough for robust analysis of adverse immune responses in humans, corneal transplantation (CT) is a well-established allogeneic tissue transplant with >100,000 full- an ...
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12
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TERMINÉ
European Consortium for High-Throughput Research in Rare Kidney Diseases (EURENOMICS)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
EURenOmics will integrate several established consortia devoted to rare kidney diseases with eminent need and potential for diagnostic and therapeutic progress (i.e. steroid resistant nephrotic syndrome, membranous nephropathy, tubulopathies, complement disorders such a haemolytic uraemic syndrome, and congenital kidney malformations). The Consortium has access to the largest clinical cohorts asse ...
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29
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TERMINÉ
Innovative, mechanistic-based strategies for delivery of therapeutic macromolecules across cellular and biological barriers (PathChooser)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
Nanomedicine offers capability to significantly change the course of treatment for life-threatening diseases. Many of the most significant current therapeutic targets, to be viable in practice, require the efficient crossing of at least one biological barrier. However, the efficient and controlled crossing of the undamaged barrier is difficult. The range of small molecules that can successfully do ...
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9
Participants partenaires
TERMINÉ
Enhanced exposure assessment and omic profiling for high priority environmental exposures in Europe (EXPOSOMICS)
Date du début: 1 nov. 2012, Date de fin: 30 avr. 2017,
This project aims to predict individual disease risk related to the environment, by characterizing the external and internal exposome for common exposures (air and drinking water contaminants) during critical periods of life, including in utero. A large amount of health data is now available from longitudinal cohorts in both children and adults, with detailed information on risk factors, confounde ...
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15
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TERMINÉ
A Gateway to European Kidney Research Resources - KidneyConnect (KidneyConnect)
Date du début: 1 août 2013, Date de fin: 31 juil. 2016,
Diabetes, Cardiovascular and Chronic kidney (DCC) -diseases are relentlessly increasing globally, causing enormous human suffering, premature deaths and unsustainable costs. Leading European research has indisputably pointed that the kidney filtration barrier and its epithelial cell, the podocyte, is a common denominator for the DCC-diseases. However, European excellence and expertise have remaine ...
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19
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TERMINÉ
Genomic & Epigenomic Complex Disease Epidemiology (GEoCoDE)
Date du début: 1 mars 2010, Date de fin: 28 févr. 2014,
Genetic and epigenetic epidemiology are rapidly developing aspects of population-based health research that have clear translational potential. These endeavours both benefit considerably from extensive international collaborations. Establishing robust associations between genetic variation and common complex disease phenotypes requires very large sample sizes than can only realistically be generat ...
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9
Participants partenaires
TERMINÉ
Synthetic Biology for Human Health: Ethical and Legal Issues (SYBHEL)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2012,
Synthetic Biology (SynBio) is a relatively new field of scientific endeavour. Rather than seeking to understand living organisms, SynBio researchers aim to design and build entirely new living systems at the molecular, cellular, tissue and organism level. SynBio uses methods and tools from many disciplines, notably engineering, genetics, biotechnology and biochemistry; but also nanotechnology, phy ...
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