7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
iABC Programme (IABC PROGRAMME)
Date du début: 1 août 2015, Date de fin: 31 juil. 2020,
...oups combine experience and proven expertise and success in microbiology, antibiotic development, clinical trials, endpoints and patient registries. Their existing infrastructure provides an excellent basis for the successful achievement of the objectives of ND4BB Topic 7. The iABC consortium will build on and add to existing research networks and infrastructures within the IMI ND4BB-program, ther ...
Voir le projet
21
Participants partenaires
TERMINÉ
Clonidine for Sedation of Paediatric Patients in the Intensive Care Unit (CloSed)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,
The majority of critically ill children admitted to Paediatric Intensive Care Units (PICU) will require sedation and analgesia which is commonly achieved with a combination of an benzodiazepine and an opioid. However, these agents have a significant side-effect profile, including tolerance, withdrawal and respiratory/circulatory depression. Clonidine is commonly used for sedation in PICU and recom ...
Voir le projet
10
Participants partenaires
TERMINÉ
Labeling of Enalapril from Neonates up to Adolescents (LENA)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Children are often treated as small adults—not as the special patients they are. Regulations exist to encourage the development of drugs and formulation for children. However, off-patent drugs are often administered to children without appropriate formulations or systematic investigations. Therefore, the paediatric use marketing authorisation (PUMA) has been designed.The EMA Paediatric Working Par ...
Voir le projet
14
Participants partenaires
TERMINÉ
PanCare Studies in Fertility and Ototoxicity to Improve Quality of Life after Cancer during Childhood, Adolescence and Young Adulthood (PANCARELIFE)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Survival rates after childhood cancer now reach nearly 80% in developed European countries as a result of more effective therapies and better supportive care, leading to a steady increase in the number of survivors in the population. However, the treatments that have improved survival are harsh and cause serious side-effects that can greatly impact survivors’ quality of life in the long term. The ...
Voir le projet
19
Participants partenaires
TERMINÉ
GAbapentin in Paediatric Pain (GAPP)
Date du début: 1 juil. 2013, Date de fin: 30 juin 2017,
Chronic pain is estimated to affect 15-20% of children with varying disabilities. Due to the paucity of clinical information and appropriate medicinal products, in clinical practice paediatric patients are often under-treated causing profound impact on their QoL.To date, opioids, non-steroid anti-inflammatory drugs (NSAIDs), antidepressants and anticonvulsants are used to treat pain, but only few ...
Voir le projet
16
Participants partenaires
TERMINÉ
New Models for Preclinical Evaluation of Drug Efficacy in Common Solid Tumours (PREDECT)
Date du début: 1 févr. 2011, Date de fin: 30 avr. 2016,
Traditional preclinical discovery methods, particularly for target validation, poorly predict drug efficacy, causing a high attrition rate in costly late-stage clinical trials. The PREDECT consortium will focus on complex but transferable, next generation in vitro and in vivo models for breast, prostate and lung cancers. Models will be investigated for their improved potential to validate novel th ...
Voir le projet
23
Participants partenaires
TERMINÉ
Prostate Research Organizations-Network of Early Stage Training (PRO-NEST)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,
"New and recent developments have revolutionized the prostate cancer research and clinical arenas, requiring the next generation scientists to have comprehensive knowledge and expertise in basic, clinical and applied research. PRO-NEST offers young researchers a European integrated, multi-disciplinary training programme to become an independent and all-round scientist and team leader in (prostate) ...
Voir le projet