8 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior (MyNewGut)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,
Emerging evidence indicates that the gut microbiome contributes to our ability to extract energy from the diet and influences development and function of the immune, endocrine and nervous systems, which regulate energy balance and behaviour. This has led to hypothesize that developing microbiome-based dietary interventions can be cost-effective measures to prevent diet-related and behavioural diso ...
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30
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TERMINÉ
Health and Environment-wide Associations based on Large population Surveys (HEALS)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
Assessing individual exposure to environmental stressors and predicting health outcomes implies that both environmental exposures and epi/genetic variations are reliably measured simultaneously. HEALS (Health and Environment-wide Associations based on Large population Surveys) brings together in an innovative approach a comprehensive array of novel technologies, data analysis and modeling tools th ...
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37
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TERMINÉ
A Unified Approach to Evaluating Cellular Immunotherapy in Solid Organ Transplantation (THE ONE STUDY)
Date du début: 1 nov. 2010, Date de fin: 31 oct. 2017,
Preventing immunological rejection of transplanted organs without the need for long-term use of pharmacological immunosuppression is a primary objective in transplantation medicine. Reducing the need for immunosuppression would dramatically improve the outcome for transplant recipients and reduce health costs for society. The means to achieve this goal has not been realised with pharmacological or ...
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16
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TERMINÉ
Personalized minimization of immunosuppression after solid organ transplantation by biomarker-driven stratification of patients to improve long-term outcome and health-economic data of transplantation (BIO-DrIM)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
Organ transplantation has emerged as the “gold standard” therapy for end-stage organ failure. Incomplete control of chronic allograft injury but also the adverse effects of long-term immunosuppression (IS) continue to challenge the long-term success of transplantation. The paradigm is shifting from increasing “net”-IS by novel drugs to the concept of minimizing long-term IS as early as possible. H ...
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17
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TERMINÉ
Improving HSCT By Validation Of Biomarkers & Development Of Novel Cellular Therapies (CELLEUROPE)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
Novel transplant regimens are currently being developed to improve beneficial GvL effects and reduce GvHD and infections via several new forms of cellular therapies. This newly emerging supra-disciplinary field of cellular therapy and regenerative medicine is also being used to improve outcomes in autoimmune disease (such as Rheumatoid Arthritis) and cancers. The goal of this research programme is ...
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13
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TERMINÉ
Cost effective Direct to Eye prosthesis SMART Guidance System (D2EYE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2016,
Approximately 800,000 hip operations are performed annually in Europe. In 56% of these operations, the components, in particular the cup, are not aligned correctly; this misalignment alters the biomechanics of the system, such that excessive wear of the cup occurs. The subsequent reduction in implant lifespan will affect ~450,000 European citizens, an average of 30,000 per year. In financial terms ...
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11
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TERMINÉ
THERAPEUTIC AND PREVENTIVE IMPACT OF NUTRITIONAL LIPIDS ON NEURONAL AND COGNITIVE PERFORMANCE IN AGING, ALZHEIMER’S DISEASE AND VASCULAR DEMENTIA (LIPIDIDIET)
Date du début: 1 août 2008, Date de fin: 31 mars 2015,
Major objective: It is our aim to develop a lipid based diet that is able to delay or prevent onset of Alzheimer’s disease and related diseases and has a stabilizing effect on cognitive performance in aging. Multiple lines of evidence suggest that there is a large overlap between risk factor of these three diseases. Importantly, there is equally strong evidence that prevention and treatment of the ...
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19
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TERMINÉ
The impact of Regulation (EC) No 1394/2007 on the development of Advanced Therapy Medicinal Products (ATMPs): an academic perspective (Academic GMP)
Date du début: 1 sept. 2010, Date de fin: 31 mai 2013,
Advanced Therapy Medicinal Products (ATMPs) are medicinal products for human use, based on gene therapy, somatic cell therapy or tissue engineering. A rapidly growing area in translational research, they represent the ‘next generation’ of complex medicines for complex diseases and pose particular challenges to medicines regulation.Regulation (EC) No 1394/2007 has been designed to ensure the free m ...
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