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Plus de 40 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

Persistent virus infection as a cause of pathogenic inflammation in type 1 diabetes - an innovative research program of biobanks and expertise (PEVNET)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,

"Type 1 diabetes is caused by an inflammatory process which damage insulin-producing beta-cells in the pancreas. It is one of the most common chronic diseases and its incidence is rapidly increasing. Due to its complications it causes a significant medical and economic burden to European society. A causal association between enterovirus and type 1 diabetes has become more and more likely. The aim ...
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 14

 TERMINÉ 

Post-infectious immune reprogramming and its association with persistence and chronicity of respiratory allergic diseases (PreDicta)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2016,

Chronic inflammatory diseases associated with allergy, including asthma and rhinitis, constitute a major and continuously growing public health concern for Europe. However, the causative factors and mechanisms converting a physiological inflammatory reaction to a chronic response triggering allergic disease remain elusive.Viral infections, particularly those caused by human rhinoviruses (RV) are t ...
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 13

 TERMINÉ 

Optimising plant polyphenols in LEGUMES for ruminant nutrition PLUS health PLUS environmental sustainability (LEGUMEPLUS)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

Europe must face the Grand Challenges of climate change and global warming, which will seriously affect the production of foods, including animal feeds. Tightening supplies of energy, foods and feeds will further impact on food security. Feeding animals in Europe with large quantities of imported soyabeans is not sustainable. ‘Home-grown’ protein sources, such as forage legumes, offer a valuable a ...
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 8

 TERMINÉ 

International Network for Terrestrial Research and Monitoring in the Arctic (INTERACT)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

Environmental change and particularly amplified global climate change are accelerating in the Arctic. These changes already affect local residents and feedback from the Arctic’s land surface to the climate system, will have global implications. However, climate change and its impacts are variable throughout the wide environmental and land use envelopes of the Arctic. Unfortunately, the Arctic is g ...
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 34

 TERMINÉ 

SUrrogate markers for vascular Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2015,

Diabetes mellitus is a lifelong, incapacitating disease affecting multiple organs. Worldwide prevalence figures estimate that there will be 246 million diabetic patients in 2007 and 380 million in 2025. Presently, diabetes can neither be prevented nor cured and the disease is associated with devastating chronic complications including coronary heart disease and stroke (macrovascular disease) as we ...
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 27

 TERMINÉ 

Translation Research Training: An integrated and intersectoral model for Europe (TIME)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

Faced with important social, professional and technological developments, research training in translation and multilingual/multimedia communication must meet new needs and develop common strategies between private/public institutions and academia. TIME will create a unique training platform to meet these needs.General objectives1. To train four ESRs and one ER to become experts in translation and ...
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 4

 TERMINÉ 

Developmental Origins of Healthy and Unhealthy Ageing: The Role of Maternal Obesity (DORIAN)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2014,

Europe has the highest proportion of elderly people in the world. Cardiovascular disease (CVD), type 2 diabetes (T2D), sarcopenia and cognitive decline frequently coexist in the same aged individual, sharing common early risk factors and being mutually reinforcing. Obesity is a main health concern in the world. In the EU one-third of women of reproductive age are overweight and 20% are obese, a pr ...
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 10

 TERMINÉ 

Chemical Bioanalysis (CHEBANA)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2014,

Chemical Bioanalysis aims for retrieving selective information out of complex biological systems. Sensors, probes and devices are the future tools of medicinal diagnostics, environmental monitoring, food analysis and molecular biology. The ITN CHEBANA provides interdisciplinary research training for early stage and experienced researchers and focuses on the most important techniques in the field. ...
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 13

 TERMINÉ 

Understanding the evolutionary mechanisms of invasion success: Selective footprints in the genome of an Euro-invader – the raccoon dog (Nyctereutes procyonoides) (EUROINVADERS)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2014,

"It is a worldwide, worrisome phenomenon that faunal endemism is threatened by introduced species populating new habitats, a process that is aided by the growing globalization which makes natural dispersal barriers more permeable. One of the most successful invaders of Europe is the raccoon dog (Nyctereutes procyonoides), a mammal that severely affects endemic biodiversity while thriving in new en ...
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 1

 TERMINÉ 

The Preparatory Phase for the Cherenkov Telescope Array (CTA-PP) (CTA-PP)

Date du début: 1 oct. 2010, Date de fin: 31 août 2014,

"The Cherenkov Telescope Array CTA will be the first open facility for gamma-ray astronomy in thevery-high-energy domain, with a performance which is dramatically improved over existing instruments in terms of sensitivity, energy coverage, survey capability and flexibility. CTA will probe non-thermal phenomena in the Universe – known to have comparable energy content to other forms of energy ...
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 20

 TERMINÉ 

Recognition and Cleavage of Biological Phosphates – Molecular Recognition, Mechanism and Biomedical Applications (PhosChemRec)

Date du début: 1 juil. 2010, Date de fin: 30 juin 2014,

Chemical Biology is a new, supradisciplinary field that unites the classically separate disciplines of Chemistry and Biology. This network is centred around understanding the central biological process of phosphate transfer and combines leading experts in synthetic chemistry, enzyme model building, kinetic analysis, protein chemistry and directed evolution in a concerted effort to gain a quantitat ...
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 10

 TERMINÉ 

Integrated whole blood acoustophoresis and homogeneous nucleic acid detection cartridge for rapid sepsis diagnostics (ACUSEP)

Date du début: 1 déc. 2010, Date de fin: 31 mai 2014,

The objective of the ACUSEP research project is to develop an integrated, dry-reagent based disposable ready-to-use cartridge enabling rapid analysis of sepsis-causing organisms and eventual identification of antibiotic resistance directly from suspected blood samples. Sepsis causes annually up to 135 000 deaths in Europe and the early diagnosis is the key to improved survival. Identification of t ...
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 5

 TERMINÉ 

Pathogenesis of Type 1 Diabetes - Testing the Hygiene Hypothesis (DIABIMMUNE)

Date du début: 1 mars 2008, Date de fin: 28 févr. 2014,

"Preliminary data indicate that there is a strong association between the incidence of immune-mediated diseases and improving standard of living and hygiene. One of the steepest gradient in standard of living worldwide is present at the border between Russian Karelia and Finland with a sevenfold difference in the gross national product, while Estonia represents a country in rapid transition. These ...
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 12

 TERMINÉ 

The influence of Aryl hydrocarbon receptor ligands on protective and pathological immune responses (AHRIMMUNITY)

Date du début: 1 févr. 2009, Date de fin: 31 janv. 2014,

The Aryl hydrocarbon receptor is an evolutionary conserved widely expressed transcription factor that mediates the toxicity of a substantial variety of exogenous toxins, but is also stimulated by endogenous physiological ligands. While it is known that this receptor mediates the toxicity of dioxin, this is unlikely to be its physiological function. We have recently identified selective expression ...
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 3

 TERMINÉ 

Data Services and Analysis Tools for Solar Energetic Particle Events and Related Electromagnetic Emissions (SEPServer)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2013,

The SEPServer project will address the topic SPA.2010.2.1-03, Exploitation of space science and exploration data, of the call FP7-SPACE-2010-1. Through its impact, the project may also support other projects funded through the topic SPA.2010.2.3-01, Security of space assets from space weather events.The main objective of the SEPServer project is to produce a new tool, which greatly facilitates the ...
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 11

 TERMINÉ 

Membrane Enhanced Tide Synthesis - A New Paradigm Peptide / Oligonucleotide Synthesis Technology (MEMTIDE)

Date du début: 1 déc. 2009, Date de fin: 30 nov. 2013,

"The MemTide Initial Training Network will create a new generation of synthesis technologies for peptide and oligonucleotide (“tide”) manufacture, with focus on the use of emerging membrane technology to effect critical separations. New nanofiltration membranes with improved chemical stability, and closely controlled molecular discrimination properties, will be developed. Novel synthesis strategie ...
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 7

 TERMINÉ 

Systems Biology of T-cell Activation in Health and Disease (SYBILLA)

Date du début: 1 avr. 2008, Date de fin: 30 sept. 2013,

T-cell activation, whether induced by pathogens or auto-antigens, is a complex process relying on multiple layers of tightly controlled intracellular signalling modules that form an intricate network. Defects in this network can cause severe and chronic disorders such as autoimmune diseases. Although 5% of the population suffer from these diseases, only a few therapeutic treatments are available. ...
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 22

 TERMINÉ 

Improving health services for European citizens with dementia: Development of best practice strategies for the transition from ambulatory to institutional long-term care facilities (RightTimePlaceCare)

Date du début: 1 janv. 2010, Date de fin: 30 sept. 2013,

Given the increasing number of patients/consumers with dementia, political action is urgently required to prepare the health care services throughout Europe to deliver cost effective high quality long-term care to people concerned. Currently there is a lack of clinical research data of patients/consumers and informal caregivers to develop best practice strategies for long-term care. RightTimePlace ...
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 8

 TERMINÉ 

Prostate Research Organizations-Network of Early Stage Training (PRO-NEST)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,

"New and recent developments have revolutionized the prostate cancer research and clinical arenas, requiring the next generation scientists to have comprehensive knowledge and expertise in basic, clinical and applied research. PRO-NEST offers young researchers a European integrated, multi-disciplinary training programme to become an independent and all-round scientist and team leader in (prostate) ...
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 18

 TERMINÉ 

Control of Light Use Efficiency in Plants and Algae - From Light to Harvest (HARVEST)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,

"Photoprotection against excess absorbed light energy is an essential and universal attribute of oxygenic photosynthetic organisms. This requirement has been a strong force in the evolution of plants and micro-organisms, and a diverse range of solutions have arisen. It has determined survival, productivity and habitat preference, and it determines the ceiling on the efficiency of energy conversion ...
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 18

 TERMINÉ 

NANOPARTICLES FOR THERAPY AND DIAGNOSIS OF ALZHEIMER DISEASE (NAD)

Date du début: 1 sept. 2008, Date de fin: 31 août 2013,

The search for effective therapies and early detection strategies for Alzheimer’s Disease (AD), the major cause of dementia in Europe, is imperative. It is known that β-amyloid (Aβ) peptide plays a central role in neurodegeneration. In AD brain, Aβ is released in a soluble form that progressively becomes insoluble forming aggregates; extracellular plaques mainly composed of Aβ are a hallmark of po ...
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 19

 TERMINÉ 

Spatially and temporally regulated membrane complexes in cancer cell invasion and cytokinesis (CANCER SIGNALOSOMES)

Date du début: 1 août 2008, Date de fin: 31 juil. 2013,

Cancer progression, characterized by uncontrolled proliferation and motility of cells, is a complex and deadly process. Integrins, a major cell surface adhesion receptor family, are transmembrane proteins known to regulate cell behaviour by transducing extracellular signals to cytoplasmic protein complexes. We and others have shown that recruitment of specific protein complexes by the cytoplasmic ...
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 2

 TERMINÉ 

Antigenic landscape analysis of dengue virus serotypes (ALADVS)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2013,

"Dengue is a mosquito-borne viral disease, which has become an important international public health problem. Dengue can be caused by any of the four closely related, yet antigenically distinct serotypes of dengue viruses (DENV-1, -2, 3 and -4) that are members of family Flaviviridae (genus flavivirus). DENV causes disease ranging from mild dengue fever, to the potentially fatal dengue hemorrhagic ...
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 1

 TERMINÉ 

Conservation Genetic Resources for Effective Species Survival (CONGRESS)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2013,

Genetic biodiversity is recognised by the Convention on Biological Diversity and the EC Biodiversity Strategy as one of three essential elements of living diversity, yet it is poorly represented at the policy level, compared to the two other components, species and ecosystems. The CONGRESS consortium aims to rectify this situation by delivering dissemination tools which policy makers and conservat ...
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 13

 TERMINÉ 

"Governance of Educational Trajectories in Europe. Access, coping and relevance of education for young people in European knowledge societies in comparative perspective" (GOETE)

Date du début: 1 janv. 2010, Date de fin: 31 mars 2013,

"The GOETE project will analyse the role of school in re-conceptualising education in terms of lifelong learning by combining a life course and a governance perspective. In European knowledge societies adequacy of education means a balance of individual, social and economic aspects. This is operationalised by exploring how educational institutions conceptualise and organise individual educational ...
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 14

 TERMINÉ 

Privacy - Appraising Challenges to Technologies and Ethics (PRACTIS)

Date du début: 1 janv. 2010, Date de fin: 31 mars 2013,

The vision that motivates PRACTIS is of a society that is aware of the evolving challenges to privacy posed by emerging technologies and is equipped to respond to them. PRACTIS will assess the potential impacts on privacy from emerging technologies and new scientific knowledge. It will propose ethical frameworks and legal procedures for coping with potential risks to privacy. It will explore novel ...
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 8

 TERMINÉ 

Use of innovative strategies for beta-cell imaging in diabetes mellitus (BetaImage)

Date du début: 1 oct. 2008, Date de fin: 31 mars 2013,

The development of sensitive, non-invasive methods for the characterisation and quantification of beta-cell mass would greatly enhance our means for gaining understanding of the pathophysiology of diabetes and allow the development of novel therapies to prevent, halt and reverse the disease. The aim of this project is to develop and apply innovative approaches for beta-cell imaging, the emphasis b ...
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 10

 TERMINÉ 

Prostate cancer: profiling and evaluation of ncRNA (ProspeR)

Date du début: 1 févr. 2008, Date de fin: 31 juil. 2012,

Annually, over 200 000 new prostate cancer cases are diagnosed in Europe. This number is expected to further increase due to widespread use of prostate specific antigen (PSA) tests on asymptomatic men and an aging population. This leads to high rate of over-detection, where most cases will never experience cancer symptoms during their lifetime. Hence, our current lack of means to predict prostate ...
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 8

 TERMINÉ 

Chloroplast Signals (COSI)

Date du début: 1 juil. 2008, Date de fin: 30 juin 2012,

"COSI integrates young researchers in a network of 10 leading European research centres, including Bayer BioScience as industrial partner. We aim at identification of regulatory principles governing chloroplast metabolism, a crucial factor for agricultural productivity. Specifically we want to identify chloroplast-related protein kinases and their targets and associated calcium signals. A long ter ...
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 13

 TERMINÉ 

Integrating and Developing European Asian Studies (IDEAS)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2012,

"Many EU and non-EU governments have concluded that the Humanities and Social Sciences could and should make a greater contribution to public policy making. For instance, the Pentagon has recently admitted that top US decision-makers were not sufficiently informed about the cultural background of Iraq when they planned the 2003 US-led invasion. Cultural perspective is essential in foreign policy-m ...
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 8

 TERMINÉ 

Evaluation of Integrated Cardiac Imaging for the Detection and Characterization of Ischemic Heart Disease (EVINCI-study)

Date du début: 1 janv. 2009, Date de fin: 30 juin 2012,

The main purpose of the EVINCI-study is to test the impact of combined “anatomo-functional” non invasive cardiac imaging for detection and characterization of Ischemic Heart Disease (IHD). The EVINCI-study is a prospective clinical European multicenter trial performed in a cohort of 700 patients with suspected IHD. Patients with intermediate pre-test probability will undergo clinical and biohumora ...
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 22

 TERMINÉ 

Ultra-high resolution and ultra-sensitive fluorescence methods for objective sub-cellular diagnosis of early disease and disease progression in breast and prostate cancer (FLUODIAMON)

Date du début: 1 juin 2008, Date de fin: 31 mai 2012,

"The overall objective of this proposal is to develop and validate a quantitative, minimally invasive diagnostic tool for early and conclusive detection, diagnosis and monitoring of disease and disease progression of breast and prostate cancer. A methodology will be developed making use of a combination of the probably most exciting recent advances in the field of light microscopy, for fluorescenc ...
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 12

 TERMINÉ 

Developmental effects of environment on reproductive health (DEER)

Date du début: 1 mai 2008, Date de fin: 30 avr. 2012,

"The multidisciplinary research teams in this consortium have played lead roles in establishing that fetal and childhood periods are vulnerable to environmental disruption leading to common reproductive disorders. This proposal will investigate: (1) connections between normal/abnormal perinatal reproductive development and maturation of reproductive function at puberty and in adulthood; (2) system ...
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 9

 TERMINÉ 

European Solar-Fuel Initiative - Renewable Hydrogen from Sun and Water. Science Linking Molecular Biomimetics and Genetics (SOLARH2)

Date du début: 1 févr. 2008, Date de fin: 31 janv. 2012,

"SOLAR-H2 brings together 12 world-leading European laboratories to carry out integrated, basic research aimed at achieving renewable hydrogen (H2) production from environmentally safe resources. The vision is to develop novel routes for the production of a Solar-fuel, in our case H2, from the very abundant, effectively inexhaustible resources, solar energy and water. Our multidisciplinary experti ...
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 12

 TERMINÉ 

interconnecting Knowledge for the early identification of issues, events and developments (e.g. wild cards and associated weak signals) shaping and shaking the future of STI in the ERA (iKnow)

Date du début: 1 nov. 2008, Date de fin: 31 oct. 2011,

In recent years, Foresight has emerged as a key instrument for the development and implementation of research and innovation policies with long-term perspectives. Much futures work and Foresight exercises are little more than extrapolations. Some activities show an interesting mix of approaches combining three types of elements: prospective studies of long-term opportunities and alternatives, part ...
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 8

 TERMINÉ 

Promotional Platform for Short Sea Shipping and Intermodality (PROPS)

Date du début: 1 juil. 2008, Date de fin: 31 oct. 2011,

The PROPS project builds on previous EU and national activities undertaken to promote and develop short sea shipping. In particular, PROPS aims to work closely with the Short Sea Promotion Centres (SPCs) to develop a workable and replicable methodology that will enhance their practical promotion activities – in the fields of legislative, technical, and operational actions – and to extend their ope ...
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 16

 TERMINÉ 

Advancing understanding of Atlantic Salmon at Sea: Merging Genetics and Ecology to resolve Stock-specific Migration and Distribution patterns (SALSEA-Merge)

Date du début: 1 avr. 2008, Date de fin: 31 oct. 2011,

Over the past two decades, an increasing proportion of North Atlantic salmon are dying at sea during their oceanic feeding migration. The specific reasons for the decline in this important species are as yet unknown, however, climate change is likely to be an important factor. In some rivers in the southern part of the salmons range, wild salmon now face extinction. This is in spite of unprecedent ...
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 20

 TERMINÉ 

PAthways for Carbon Transitions (PACT)

Date du début: 1 oct. 2008, Date de fin: 30 sept. 2011,

Most «business-as-usual scenarios» built up till now have shown that hydrocarbon resources scarcity and the growing release of greenhouse gases will bring the world far away from sustainability over the next decades. Then, deep changes in behaviours away from «BAU» are unavoidable long before the turn of the century in a move towards a post-carbon society. Urbanisation and mobility are probably ...
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 12

 TERMINÉ 

Comprehensive assessment of hazardous effects of engineered nanomaterials on the immune system (NANOMMUNE)

Date du début: 1 sept. 2008, Date de fin: 31 août 2011,

Engineered nanomaterials (ENs) present tremendous opportunities for industrial growth and development, and hold great promise for the enrichment of the lives of citizens, in medicine, electronics, and numerous other areas. However, there are considerable gaps in our knowledge concerning the potential hazardous effects of ENs on human health and the environment. Our EU-US partnership is committed t ...
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 10

 TERMINÉ 

Novel strategic approach to design better vaccines (INNOVAC)

Date du début: 1 sept. 2009, Date de fin: 31 août 2011,

"The structure and thermodynamic properties of Y. pestis capsular Caf1 antigen were studied to explain the failure of this protein to induce the cellular immune response. During the assembling of the Caf1 capsule, the collapse of Caf1 hydrophobic core results in the formation of extremely stable Caf1 fibers. This increases resistance of the Caf1 antigen to processing in macrophages and thereby abo ...
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 1