1 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
DEFINING THE MECHANISMS OF AGE-RELATED MUSCLE LOSS: FOCUS ON AUTOPHAGY (MyoPHAGY)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2016,
Muscle loss occurs in many diseases including cancer, AIDS, diabetes, renal or cardiac failure and sepsis. The wasting of muscle mass is characterized by the activation of an atrophy program that coordinates the ubiquitin-proteasome and autophagy-lysosome systems. The simultaneous activation of these systems allows the breakdown of contractile proteins and the removal of organelles. Ageing sarcope ...
Voir le projet