4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
An integrated interdisciplinary approach to animal-free chemical and nanomaterial safety assessment (in3)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
All chemicals whether they are drugs, cosmetics, agrochemicals or others need to be tested for their safety to man and the environment. The use of whole animal studies for the prediction of adverse effects in man, is problematic due to species dependent effects, high costs and a large burden to animals in terms of numbers and suffering. While there have been major improvements in human in vitro a ...
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14
Participants partenaires
TERMINÉ
Systems biology for the functional validation of genetic determinants of skeletal diseases (SYBIL)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
"The aim of SYBIL is to carry out extensive functional validation of the genetic determinants of rare and common skeletal diseases and the age related factors contributing to these painful conditions. To achieve this goal SYBIL will gather complementary translational and transnational scientists, systems biologists, disease modellers, leading SMEs and industrialists that will perform in-depth char ...
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19
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TERMINÉ
Utility of omic-based biomarkers in characterizing older individuals at risk for frailty, its progression to disability and general consequences to health and well-being - The FRAILOMIC Initiative (FRAILOMIC)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
The forecasted increase in the number of older people for this century will be accompanied by an increase of those with disabilities. Disability is usually preceded by a condition named frailty that encompasses changes associated with ageing, life styles and chronic diseases. To detect and intervene on it is of outstanding importance to prevent disability, as recovery from disability is unlikely. ...
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29
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TERMINÉ
Nanoscopically-guided induction and expansion of regulatory hematopoietic cells to treat autoimmune and inflammatory processes (NanoII)
Date du début: 1 déc. 2009, Date de fin: 30 nov. 2013,
We propose a multidisciplinary program, focusing on the development of novel approaches for directing the differentiation, proliferation and tissue-tropism of specific hematopoietic lineages, using micro- and nano-fabricated cell chips. We will use advanced nanofabricated surfaces functionalized with specific biomolecules, and microfluidics cell chips to specify and expend regulatory immune cells ...
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