2 projets européens trouvés
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TERMINÉ
"The Singlet Oxygen Strategy: sustainable oxidation procedures for applications in material science, synthesis, wastewater treatment, diagnostics and therapeutics" (SO2S)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
"The SO2S network seeks to exploit Singlet Oxygen (1O2) as a green and benign oxidant for use in novel synthetic methodologies, crosslinking strategies, bioconjugation procedures and materials production. The chemistry described herein generates the means to both understand and influence biological systems by providing probes and reagents – from analytical methods to new drugs - and to modulate ma ...
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TERMINÉ
Inhibiting Nef: a novel drug target for HIV-host interactions (iNEF)
Date du début: 1 janv. 2008, Date de fin: 30 juin 2011,
Although HIV-1 Nef was originally named "negative factor," it has been shown to be critical for efficient persistance of HIV-1 infected humans thus playing a major role in the progression to AIDS. Remarkably; until now Nef has not been evaluated as an antiretroviral drug target. It is well established that Nef promotes HIV-1 replication and facilitates viral immune evasion by interacting with vari ...
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