11 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)
Date du début: 1 oct. 2013, Date de fin: 31 mars 2020,
Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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44
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TERMINÉ
Protein S-mycothiolation and real-time redox imaging in Corynebacterium diphtheriae during ROS stress and infection conditions (MYCOTHIOLOME)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,
Glutathione serves as the major thiol-redox buffer in the defense against Reactive Oxygen Species (ROS) in eukaryotes. Firmicutes bacteria utilize as thiol redox buffer bacillithiol (Cys-GlcN-Mal, BSH) and Actinomycetes produce the related redox buffer mycothiol (AcCys-GlcN-Ins, MSH). In eukaryotes, proteins are post-translational modified to S-glutathionylated proteins in response to oxidative st ...
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2
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TERMINÉ
Synthesis of mono-dithiolene molybdenum complexes and their evaluation as potential drugs for the treatment of human isolated sulfite oxidase deficiency (MOCOMODELS)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2018,
Two rare but usually fatal diseases are caused by a failure at different levels of the multistep biosynthetic generation of the three human molybdenum dependent enzymes involved in metabolic processes. In contrast to the more general Moco deficiency (MocoD) affecting all three enzymes, isolated sulfite oxidase deficiency (iSOD) cannot be treated yet. The proposed project is primarily aimed at synt ...
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3
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TERMINÉ
Creating Economic Space for Social Innovation (CRESSI)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
"The CRESSI project will explore the economic underpinnings of social innovation with a particular focus on how policy and practice can enhance the lives of the most marginalized and disempowered citizens in society. Overall, the bid will take an institutionalist view of the key issues exploring the drivers and structures that lead to marginalization and disempowerment and then setting out how int ...
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9
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TERMINÉ
Oral biopharmaceutics tools (ORBITO)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
The OrBiTo project will deliver novel methods and a framework for rational application of predictive biopharmaceutics tools for oral drug delivery. This will be achieved through novel propsective studies to define new methodlogies which will be validated using historical datasets from EFPIA partners. A combination of high quality in vitro or in silico characterizations of API and formulations will ...
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28
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TERMINÉ
Advanced Multidisciplinary Training in Molecular Bacteriology (AMBER)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
"The advancement in life sciences has created a growing number of disciplines that are required to elucidate the increasingly complicated biological questions. This has led to an unsurpassed level of knowledge, but it has also resulted in a continuous specialization in PhD trainings, which makes the students less prepared for complex present day biological questions. To provide a better comprehens ...
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9
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TERMINÉ
Nanoelectronic COupled Problems Solutions (nanoCOPS)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,
Designs in nanoelectronics often lead to problems that are large to simulate and that include strong feedback couplings. Industry demands to include variability to guarantee quality and yield. It also requests to incorporate higher abstraction levels to allow for system simulation in order to shorten design cycles, while preserving accuracy. The nanoCOPS project considers the simulation of two pro ...
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13
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TERMINÉ
An interactive protein engineering portal with validated software and database facilities (NEWPROT)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
Two academic groups and eight SMEs who all work on different aspects of protein engineering will collaborate and produce a website that will consist of a portal with an embedded workbench to provide users a self-service system for in silico protein engineering. This interactive self-service portal will give users access to a wide variety of protein engineering facilities and information systems, a ...
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10
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TERMINÉ
MOTivational strength of ecosystem services and alternative ways to express the value of BIOdiversity (BIOMOT)
Date du début: 1 sept. 2011, Date de fin: 31 août 2015,
People in Europe acknowledge that nature is important to them and to society at large. Economists have shown that indeed, biodiversity has total economic values running into the trillions of euros worldwide and hundreds of millions even for ‘minor’ ecosystem services on local scales. In spite of these immense values, politicians and the general public in Europe do not appear to really act for natu ...
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8
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TERMINÉ
"CATO - CBRN crisis management: Architecture, Technologies and Operational Procedures" (CATO)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2014,
"CATO proposes to develop a comprehensive Open Toolbox for dealing with CBRN crises due to terrorist attacks using non-conventional weapons or on facilities with CBRN material. CATO will:• combine CBRN knowledge, planning & response know-how, DSS building blocks and dedicated models and algorithms• enable the development of specific holistic CBRN-DSS• cover the entire CBRN disaster life cycle from ...
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28
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TERMINÉ
European Network on Directed Evolution of Functional Proteins (ENEFP)
Date du début: 15 oct. 2008, Date de fin: 14 oct. 2012,
"This project intends to use directed evolution as tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. By harnessing the forces of Darwinian evolution in the laboratory we want to (i) screen large and diverse genome libraries for protein with new and useful functions, (ii) optimize existing proteins for appl ...
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