Plus de 40 projets européens trouvés
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TERMINÉ
The Great War and Modern Philosophy (GRAPH)
Date du début: 1 oct. 2014, Date de fin: 30 sept. 2019,
"The First World War was an unprecedented event of destruction, transformation, and renewal that left no aspect of European culture unchanged. Philosophy proved no exception: the war motivated an historically singular mobilization of philosophers to write about the war during the years of conflict; significant works of philosophy were written during the war years and immediately thereafter; the po ...
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TERMINÉ
Holographic Quantum Cosmology (HoloQosmos)
Date du début: 1 août 2014, Date de fin: 31 juil. 2019,
The current theory of cosmic inflation is largely based on classical physics. This undermines its predictivity in a world that is fundamentally quantum mechanical. With this project we will develop a novel approach towards a quantum theory of inflation. We will do this by introducing holographic techniques in cosmology. The notion of holography is the most profound conceptual breakthrough that has ...
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TERMINÉ
Structural Household Analysis using Revealed Preferences (SHARP)
Date du début: 1 août 2014, Date de fin: 31 juil. 2019,
"Household consumption (including labor supply) is usually the outcome of a complex interaction between multiple household members. Understanding this consumption behavior requires non-unitary modeling of households, which recognizes that households are not single decision units but consist of interacting individuals. This project builds a powerful toolkit for empirical analysis of household consu ...
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TERMINÉ
Rigidity and classification of von Neumann algebras (RIGIDITY)
Date du début: 1 juil. 2014, Date de fin: 30 juin 2019,
"Sorin Popa's deformation/rigidity theory has lead to an enormous progress in our understanding of von Neumann algebras coming from discrete groups and their actions on probability spaces. In a five year long collaboration with Sorin Popa, we solved many long-standing open problems in this area, including superrigidity theorems for group measure space II_1 factors, results on the possible fundamen ...
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TERMINÉ
Spectroscopy of exotic nuclei in a Magnetic Active Target (SpecMAT)
Date du début: 1 juin 2014, Date de fin: 31 mai 2019,
SpecMAT aims at providing crucial experimental information to answer key questions about the structure of atomic nuclei:- What are the forces driving the shell structure in nuclei and how do they change in nuclei far from stability?- What remains of the Z = 28 and N = 50 “magic numbers” in 78Ni?- Do we understand shape coexistence in nuclei, and what are the mechanisms controlling its appearance?T ...
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1
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TERMINÉ
Cholinergic modulation of immune homeostasis: new opportunities for treatment (Cholstim)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,
In the gastrointestinal tract, the balance between activation of the mucosal immune system and tolerance should be tightly regulated to maintain immune homeostasis to prevent chronic inflammation and tissue damage. Recently, the new concept was introduced that the vagus nerve plays an important role in modulating immune homeostasis as part of a so-called inflammatory reflex. We provided evidence f ...
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TERMINÉ
KU Leuven Junior Researcher Outgoing Mobility Programme (JUMO)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
The KU Leuven Junior Researcher Mobility (JuMo) concept starts from the principle that international or intersectorial mobility is an essential part of the training of young researchers to broaden their skills and career opportunities both inside and outside academia. Young researchers grow towards more independence and research excellence through the confrontation with other cultures, ideas, scie ...
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TERMINÉ
The Role of Neuropeptides in Learning and Memory (PEPTIDELEARNING)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
"Humanity has always been intrigued by the nearly mythical properties of the brain. With its billions of neurons and innumerable connections, the brain is of such complex nature, that trying to understand it may seem a vain project. Yet, by using the ‘mini-brain’ of the model organism Caenorhabditis elegans, which shares many components with the human brain but counts only 302 neurons, thorough re ...
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1
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TERMINÉ
Ribosome defects in cancer (RIBOCANCER)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,
"Cancer cells are defective in vital cell functions such as cell cycle control and response to growth signals. We found that cancer cells acquire defects in yet another vital function: translation of mRNA into proteins. We saw that 9.8% of children with T-cell leukemia (T-ALL) harbor acquired mutations in the ribosome, the cellular protein translation factory. We found mutations in RPL10, RPL5 and ...
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2
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TERMINÉ
"The Experimental Study of Threat-Avoidance in Anxiety Patients: Behavioral, Emotional, and Neural Correlates" (TESTAAP)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2018,
"Disabling forms of anxiety are a major problem for many people world-wide and come with high societal and financial costs. Important steps forward are being made within a global network of translational trans-disciplinary and trans-diagnostic researchers. These pre-clinical research efforts focus on reducing inflated levels of fear, with considerable success. But, clinicians, clinical theorists a ...
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TERMINÉ
Motivic zeta functions and the monodromy conjecture (MOTZETA)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,
The monodromy conjecture, formulated in the seventies by the Japanese mathematician Igusa, is one of the most important open problems in the theory of singularities. It predicts a remarkable connection between certain geometric and arithmetic invariants of a polynomial f with integer coefficients. The conjecture describes in a precise way how the singularities of the complex hypersurface defined b ...
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3
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TERMINÉ
Counteracting psychosis by optimizing interaction (INTERACT)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2018,
Psychotic disorders are amongst the most severe mental disorders. However, current treatments have failed to reduce disability or change the prospects for recovery for patients with a psychotic disorder. In this project, I will investigate an entirely novel therapy, targeting the core vulnerability profile of altered person-environment interactions underlying psychosis, specifically increased stre ...
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3
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TERMINÉ
The Real Estate/Financial Complex (REFCOM)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2018,
Real estate and finance were at the roots of the global economic crisis that started in 2007. States and their many institutions have also been seen as complicit to the crisis. The connections between real estate (both residential and non-residential), finance and states still remain under-researched and under-theorized. Work in various political economy traditions has done a great deal of researc ...
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1
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TERMINÉ
Implications of the Shifting Gender Balance in Education for Reproductive Behaviour in Europe (GENDERBALL)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
This project is the first comprehensive study of the demographic consequences of a major recent development in Europe: while men have always received more education than women in the past, this gender balance in education has now turned around. For the first time in history, there are more highly educated women than men reaching the reproductive ages and looking for a partner. I expect that this w ...
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TERMINÉ
Statistically Efficient Structured Prediction for Computer Vision and Medical Imaging (STRATEGIE)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,
Inference in medical imaging is an important step for disease diagnosis, tissue segmentation, alignment with an anatomical atlas, and a wide range of other applications. However, imperfections in imaging sensors, physical limitations of imaging technologies, and variation in the human population mean that statistical methods are essential for high performance. Statistical learning makes use of h ...
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3
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TERMINÉ
Scaling-up multiphase microchemical reactors (MicroToMilli)
Date du début: 1 oct. 2013, Date de fin: 25 oct. 2017,
The aim of chemical engineering and its unit operations is to transform raw materials into products (e.g. commodity and specialty chemicals like pharmaceuticals). However, motivated by the awareness of the world’s finite resources, it is desirable that these products are obtained in a sustainable, efficient and environmentally acceptable fashion, which means minimising waste and energy use, and ma ...
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2
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TERMINÉ
Linkage mechanisms between citizens and the state. Consequences of changing value patterns and expanding participation repertoires (LINKAGE)
Date du début: 1 sept. 2012, Date de fin: 31 août 2017,
Linkage systems between citizens and the state have been transformed dramatically in previous decades. Structural linkages, like party membership, partisan identities and institutionalized forms of participation (e.g., voting) are in decline, while in a number of countries, political trust too has eroded. Research has shown, however, that this decline does not amount to an alienation of citizens f ...
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TERMINÉ
Demography, Ecology, Evolution and Management in the Deep (DEEMDEEP)
Date du début: 23 mars 2015, Date de fin: 3 juil. 2017,
The oceans, upon which humanity relies for its survival, it is largely unexplored. Recent estimates establish that only 5% of the bottom of the sea has been explored. Of this small area, only one millionth is constituted by deep sea floor. Despite being largely unknown, the deep sea is becoming exceedingly exploited, especially by fisheries searching for new stocks.For all these reasons, understan ...
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TERMINÉ
EPidemiological Left ventriclar Outcomes Research in Europe (EPLORE)
Date du début: 1 juil. 2012, Date de fin: 30 juin 2017,
Heart failure (HF) affects 15 million Europeans and entails higher mortality and health care costs than cancer. EPLORE addresses this issue by prospective epidemiological research in 4 European countries and by a proof-of-concept clinical trial. WP1 will for the first time at the population level document the incidence and progression of subclinical LV dysfunction and clarify whether asymptomatic ...
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TERMINÉ
ASAMBA: AsteroSeismic Approach Towards Understanding Massive Blue SupergiAnts (ASAMBA)
Date du début: 1 juil. 2015, Date de fin: 30 juin 2017,
"The recent space-born missions dedicated to studying stellar variabilityproviding unprecedented high-precision photometry of variable massiveAdditionally, we have also monitored a sample of oscillating blue supergiants in high-precision spectroscopy over 7 years.Such rich observational data call for carefully designed methods for astrophysical interpretation.This project aims to develop and provi ...
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1
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TERMINÉ
Genetic and epigenetic regulation of vitamin C accumulation in apple fruits (VITAFRUIT)
Date du début: 1 juil. 2015, Date de fin: 30 juin 2017,
"To date, fruit-breeding programmes have mostly focused on easily identifiable phenotypic characteristics such as fruit colour or size. However, the availability of high-throughput analytical and molecular methodologies now allows us to pursue more challenging quality traits such as nutritional contents and an increase in vitamin C concentrations. The main goal of this proposal is to identify the ...
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TERMINÉ
How the modularization of the mind unfolds in the brain (ModularExperience)
Date du début: 1 juin 2012, Date de fin: 31 mai 2017,
The mind is not an unitary entity, nor is its physical substrate, the brain. Both can be divided into multiple components, some of which have been referred to as modules. Many controversies exist in cognitive science, psychology, and philosophy about the properties and the status of these modules. A compromise view is offered by an hypothesis of modularization which has two central tenets: (i) Gen ...
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TERMINÉ
Advanced Data-Driven Black-box modelling (A-DATADRIVE-B)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,
Making accurate predictions is a crucial factor in many systems (such as in modelling energy consumption, power load forecasting, traffic networks, process industry, environmental modelling, biomedicine, brain-machine interfaces) for cost savings, efficiency, health, safety and organizational purposes. In this proposal we aim at realizing a new generation of more advanced black-box modelling tech ...
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TERMINÉ
Heavy Element Laser Ionization Spectroscopy (HELIOS)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
The aim of this proposal is to develop a novel laser-spectroscopy method and to study nuclear and atomic properties of heaviests elements in order to address the following key questions:- Is the existence of the heaviest isotopes determined by the interplay between single-particle and collective nucleon degrees of freedom in the atomic nucleus?- How do relativistic effects and isotopic composition ...
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1
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TERMINÉ
Biomimetic process design for tissue regeneration: from bench to bedside via in silico modelling (BRIDGE)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2016,
"Tissue engineering (TE), the interdisciplinary field combining biomedical and engineering sciences in the search for functional man-made organ replacements, has key issues with the quantity and quality of the generated products. Protocols followed in the lab are mainly trial and error based, requiring a huge amount of manual interventions and lacking clear early time-point quality criteria to gu ...
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2
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TERMINÉ
To the roots of induced systemic resistance in the Arabidopsis-Trichoderma-Fusarium tripartite interaction (To the roots of ISR)
Date du début: 1 oct. 2014, Date de fin: 30 nov. 2016,
Biological control organisms (BCOs) can form an important component of more sustainable agriculture. Trichoderma spp. are soil fungi with great potential in this respect. They can trigger induced systemic resistance (ISR) in the plant, leading to a more rapid and robust systemic activation of defense when the plant is subsequently challenged by a pathogen. However, genome-wide investigations of th ...
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1
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TERMINÉ
OsteoMotion: Analyzing the mechanisms and role of osteogenic cell movement in bone development and disease (OsteoMotion)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2016,
Bone development and homeostasis must incontestably rely on a correct spatial positioning of osteoblasts to generate bone at appropriate sites. A failure of osteoblasts to reach the sites in need of bone formation may contribute to impaired fracture repair and osteoporosis. Conversely, uncontrolled osteogenic cell movement may play a role in diseases involving aberrant placement of bone. Mechanism ...
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1
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TERMINÉ
A novel epigenetic modification in pluripotent stem cells (EpiPluS)
Date du début: 1 sept. 2012, Date de fin: 31 août 2016,
DNA methylation is critical during mammalian development, generally represses transcription when present at gene promoters and regulates cell lineage-specific gene expression programs. Conversely, during cellular reprogramming, efficient erasure of DNA methylation is essential for reactivation of previously silenced genes and for attaining pluripotency. The identity of such “DNA demethylase(s)” ha ...
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TERMINÉ
A general law describing the diffusion of membrane proteins in vivo based on single molecule tracking of membrane proteins in Escherichia coli (D_in_vivo)
Date du début: 1 sept. 2014, Date de fin: 31 août 2016,
The ultimate goal of cell biology is to understand how proteins function in real cells and to understand their regulatory mechanisms. To achieve this goal one needs to analyze molecules in their cellular environment and not under idealized test tube conditions. A major difference between in vivo and in vitro conditions is the crowdedness (and associated molecular complexity) of the cytoplasm and b ...
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1
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TERMINÉ
VAD-Patient interaction: from rest to exercise (VAD AND EXERCISE)
Date du début: 5 août 2014, Date de fin: 4 août 2016,
Heart failure is the first cause of death in industrialized countries. Despite the use of medical therapy a certain percentage of patients (PTs) will progress to end stage heart failure. In this case the ventricular assist device (VAD) is a viable therapy that nowadays is used increasingly not only as a bridge to transplantation, but also as destination therapy and as a bridge to recovery. Therefo ...
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1
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TERMINÉ
DOT1L in Osteoarthritis (DOTOS)
Date du début: 1 mars 2014, Date de fin: 29 févr. 2016,
The DOTOS project will study the role of DOT1L in synovial joint development, homeostasis and disease with specific attention towards osteoarthritis (OA), one of the most common chronic diseases.We identified an association between the DOT1L (DOT1-like histone H3 methyltransferase) gene and OA. Histone methylation is a regulator of gene transcription. Some histone methylations result in increased ...
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1
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TERMINÉ
Trade, Productivity, and Firm Capabilities in China's Manufacturing Sector (CHINA)
Date du début: 1 févr. 2010, Date de fin: 31 janv. 2016,
China s economy has expanded at breakneck speed to become the 3rd largest trading country in the world and the largest recipient of foreign direct investment (FDI). Entry into the WTO in 2001 was a landmark event in this ongoing process and I propose to study several channels through which it spurred China s industrial development. Crucially, I will take an integrated view of the different ways in ...
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TERMINÉ
EMULSION DESIGN TO IMPROVE NUTRITIONAL AND ORGANOLEPTIC QUALITY OF CEREAL BASED FOOD SYSTEMS (EMULSIFOOD)
Date du début: 15 janv. 2013, Date de fin: 14 janv. 2016,
In light of the alarming reports on (the evolution of) the health condition of consumers in the developed world, research and food industry environments are currently investing much time and effort in the quest for ‘healthier’ food systems. However, inclusion or in situ production of bioactive compounds in food systems to improve their nutritional profile while maintaining their organoleptic prope ...
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TERMINÉ
“Adaptation to cyanobacteria through the symbiotic microbiota in the waterflea Daphnia” (ANSWER)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2015,
Metazoans are ubiquitously associated with microbial symbionts, which can provide direct benefits to their hosts, such as nutrients provisioning, protection against environmental stress, or enhancement of host digestive abilities. These microbial mutualists have the ability to adapt rapidly to changing environments, and could potentially play a key role in the local adaptation of their host, espec ...
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TERMINÉ
Speciation through fungi? - The role of mycorrhizal associations in orchid diversification (MYCASOR)
Date du début: 1 déc. 2010, Date de fin: 30 nov. 2015,
The Orchidaceae is the most diverse family of angiosperms with an estimated number of over 24,000 species. It has long been believed that co-evolution with pollinating animals has played an instrumental role in the unparalleled diversification of the Orchidaceae. Many orchid species, however, are generalists with respect to their pollinators. Because the availability of a suitable mycorrhizal fung ...
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TERMINÉ
Objects in sight: the neural basis of visuomotor transformations for actions towards objects (BRAINSHAPE)
Date du début: 1 nov. 2010, Date de fin: 31 oct. 2015,
Humans and other primates possess an exquisite capacity to grasp and manipulate objects. The seemingly effortless interaction with objects in everyday life is subserved by a number of cortical areas of the visual and the motor system. Recent research has highlighted that dorsal stream areas in the posterior parietal cortex are involved in object processing. Because parietal lesions do not impair o ...
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TERMINÉ
New Frontiers in (Trans)esterification Pervaporation Membrane Reactors (New-PMR)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
Pervaporation membrane reactors (PMRs) have shown extraordinary potential to separate continuously water from water-organic solvent mixtures. They are applied to the separation of water in esterification reactions to shift the equilibrium towards the production of the ester. In this work, a PMR will be set up and studied to perform the esterification reaction of ethylene with acetic acid and remov ...
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2
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TERMINÉ
Deep Transfer: Generalizing Across Domains (Deep Transfer)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
Machine learning's goal is to devise algorithms that improve with experience. Currently, experience is largely defined to be the amount of available data. Unfortunately, acquiring data can be time consuming (e.g., annotating documents), monetarily expensive (e.g., genetic testing), physically invasive (e.g., collecting a tissue sample) or unavailable in sufficient quantities (e.g., data about rar ...
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TERMINÉ
Evolutionary reconstruction of viral spread in time and space (VIRALPHYLOGEOGRAPHY)
Date du début: 1 oct. 2010, Date de fin: 30 sept. 2015,
To identify the causal mechanisms leading to disease emergence, endemic maintenance and epidemic expansion,epidemiologists would benefit tremendously from a full characterization of pathogen spread in space and time. The extensivesequencing efforts for the ongoing swine-origin H1N1 influenza A epidemic testify that analyses of pathogen genetic data arebecoming increasingly important source of info ...
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3
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TERMINÉ
Handy natural ventilation rate calculator based on computational fluid dynamics (HNVR-Calculator)
Date du début: 7 août 2013, Date de fin: 6 août 2015,
Considering crop and animal production, IAQ, gas emissions, associated health effects and socio-economic problems, one of the biggest issues, these days, in Europe as well as in the world is to measure the ventilation rate of naturally ventilated buildings. Among various direct and indirect methods, the CFD approach can produce the most practical and timely solutions because of its outstanding pot ...
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