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TERMINÉ
Regulation of normal and leukaemic stem cells by the microenvironment: role of nestin+ mesenchymal stem cells and humoral signals (LSCMICROENV)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2016,
The presence of self-renewing “cancer stem cells” responsible for tumour initiation and maintenance has been well defined in multiple types of solid and haematologic tumours; however, our knowledge of their biology is very limited. While it is believed that leukaemia stem cells (LSC) – like normal haematopoietic stem cells (HSC) – depend on the interaction with a specialized microenvironment or ‘n ...
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TERMINÉ
Role of c-Myc in atherosclerotic macrophages (MycMacs)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2014,
Atherosclerosis and associated cardiovascular disease are the leading causes of mortality in developed countries and the World Health Organization has estimated that by 2020 these disorders will be the main sanitary and socio-economic problem world-wide due in part to the progressive aging of our societies. Atherosclerosis is a complex chronic inflammatory process triggered and perpetuated by card ...
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