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 TERMINÉ 

An integrated concept of tumor metastasis: implications for therapy (TuMIC)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2012,

From many perspectives our concept of the process of metastasis is inadequate and needs to be revised. In particular, the potential impact of recent ideas about the cellular basis of tumor growth (cancer stem cells) and the establishment by remote tumors of special permissive microenvironments in target organs prior to metastasis (metastatic niches) remains to be explored. In the TuMIC project we ...
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 14

 TERMINÉ 
"A Europe-wide consortium of experimental biologists, biomathematicians, biostatisticians, computer scientists and clinical scientists will team up to approach cell death pathways in health and disease, placing particular emphasis on cancer and AIDS. The consortium will create a unique database integrating existing and accumulating knowledge on lethal signal transduction pathways leading to apopto ...
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 24

 TERMINÉ 

Genomic Instability in Cancer and Precancer (GENICA)

Date du début: 1 janv. 2008, Date de fin: 31 déc. 2010,

"Genomic instability is a characteristic of practically all human cancers. Recent results generated by members of this Consortium suggest that signs of genomic instability are evident from the very beginning of human cancer development, even in precancerous lesions. In these early lesions, the genomic instability affects primarily specific genomic loci, called common fragile sites. Because common ...
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 11