4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Advanced Studies towards Knowledge on Lyssavirus Encephalitis Pathogenesis Improving Options for Survival (ASKLEPIOS)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,
The overall aim of ASKLEPIOS is to unravel and increase our understanding of the mechanisms that govern pathogenesis of rabies virus (RABV) infection, in pursuit of the rational identification of novel therapeutic leads for rabies encephalitis. Several studies have been conducted over the past decades attempting to unravel the pathogenesis of this deadly disease, however with limited success. New ...
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9
Participants partenaires
TERMINÉ
Optical dissection of cortical dopamine signaling (ODICODAS)
Date du début: 1 mai 2014, Date de fin: 30 avr. 2016,
Coordination, execution and learning of skilled movements strongly depend on motor cortex function, which, in turn, depends on the modulatory action of different neurotransmitters. In particular, dopaminergic inputs to the motor cortex have been associated with synaptic plasticity, changes in cortical excitability and modulation of cortical motor maps. The integrity of dopaminergic terminals is re ...
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1
Participant partenaire
TERMINÉ
Mucus Permeating Nanoparticulate Drug Delivery Systems (ALEXANDER)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2016,
The objective of the ALEXANDER project is the identification of novel strategies (e.g., proteolytic enzyme strategy, thiomer strategy, zeta potential changing systems, SNEDDS strategy) and the optimization of existing strategies (e.g., disulfide breaking strategy and slippery surface strategy) for the efficient transport of nanocarriers through the mucus gel layer (e.g., intestinal, nasal, ocular, ...
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20
Participants partenaires
TERMINÉ
Development of gamma-TiAl forgings in a low-cost near conventional hot-die process and process evaluation (DAFNE)
Date du début: 1 avr. 2011, Date de fin: 30 sept. 2014,
"The strong need for higher efficiency, reduced CO2 emissions and weight reduction in aircraft engines leads to a demand of innovative light-weight high-temperature resistant materials which can partly substitute the materials currently employed. Presently, Ni-base alloys are used for turbine blades in aero-engines which satisfy the high mechanical and thermal requirements. A disadvantage of Ni-ba ...
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