5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
The Role of Ectopic Adipocyte Progenitors in Age-related Stem Cell Dysfunction, Systemic Inflammation, and Metabolic Disease (AgeingStemCellFate)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,
Ageing is accompanied by ectopic white adipose tissue depositions in skeletal muscle and other anatomical locations, such as brown adipose tissue and the bone marrow. Ectopic fat accrual contributes to organ dysfunction, systemic insulin resistance, and other perturbations that have been implicated in metabolic diseases.This research proposal aims to identify the regulatory cues that control the d ...
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2
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TERMINÉ
Utility of omic-based biomarkers in characterizing older individuals at risk for frailty, its progression to disability and general consequences to health and well-being - The FRAILOMIC Initiative (FRAILOMIC)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
The forecasted increase in the number of older people for this century will be accompanied by an increase of those with disabilities. Disability is usually preceded by a condition named frailty that encompasses changes associated with ageing, life styles and chronic diseases. To detect and intervene on it is of outstanding importance to prevent disability, as recovery from disability is unlikely. ...
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29
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TERMINÉ
Global initiative on gene-environment interaction on diabetes/obesity risk (InterConnect)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
The overall goal of InterConnect is to establish a global network that will facilitate the co-ordination of population research on the interaction between genetic and environmental factors in the aetiology of obesity and diabetes. We aim to establish mechanisms for identification and classification of studies and the data that they hold and create a forum for harmonization of methods as a foundati ...
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12
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TERMINÉ
EPIC-CVD: Individualised CVD risk assessment: tailoring targeted and cost-effective approaches to Europe's diverse populations (EPIC-CVD)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
"EPIC-CVD's overarching goal is to provide clinicians and policy-makers with a menu of evidence-based options for cost-effective individualised risk assessment that enables the EU's increasingly resource-constrained economies to achieve more personalised predictive medicine in harmony with Europe's diverse cultures and healthcare systems.We will achieve this through developing and validating innov ...
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33
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TERMINÉ
European Obesity Consortium studying the Hypothalamus and its Interaction with Peripheral organs (EurOCHIP)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,
The past decade has seen tremendous progress in our understanding of homeostatic regulators controlling energy balance. Insights from human and murine genetics have illuminated multiples pathways within the hypothalamus, brainstem and higher brain regions that play a key role in the control of food intake, whilst physiological studies focusing on the gastrointestinal tract have revealed a panoply ...
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