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Physiological role of the peripheral benzodiazepine receptor and its implications in apoptotic cell-death signaling pathways (PBR AND APOPTOSIS)
Date du début: 3 mars 2008, Date de fin: 2 mars 2009,
The peripheral benzodiazepine receptor (PBR) is an 18-kDa protein receptor, mainly found on the outer mitochondrial membrane of cells. The PBR seems to play a role in several cellular functions, including heme synthesis, steroidogenesis, DNA synthesis, cell growth and differentiation.Recently, a role for PBR in apoptosis has also been proposed and a number of findings argue in favour of this:- ove ...
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