9 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Rational Bioactive Materials Design for Tissue Regeneration (BIODESIGN)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,
The development of functional materials for tissue regeneration is today mostly based on perceived and limited design criteria often using a single point approach with lengthy animal trials. The outcome after in-vitro and in-vivo evaluation is often disappointing resulting in a tedious iteration process. The main objective of this project is to achieve radical innovations in state-of-the-art bioma ...
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21
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TERMINÉ
NEURAL TRANSPLANTATION IN THE TREATMENT OF PATIENTS WITH PARKINSON’S DISEASE (TRANSEURO)
Date du début: 1 janv. 2010, Date de fin: 30 juin 2016,
There are currently no cures for Parkinson's disease (PD) but one of the most effective reparative therapies in patients to date has been with allotransplants of dopamine (DA) neuroblasts obtained from fetal ventral mesencephalic (VM) tissue. However, this cell transplantation approach has given inconsistent results, with some patients doing extremely well and coming off anti-PD medication for yea ...
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15
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TERMINÉ
Neurotrophic Cochlear Implant for Severe Hearing Loss (NeuEar)
Date du début: 1 sept. 2012, Date de fin: 31 déc. 2015,
Sixteen percent of adult Europeans suffer from hearing loss, great enough to adversely affect their daily life. Over the age of 80, 50% of the population is suffering from hearing loss. A large portion of this population is affected by sensoryneural hearing loss (SNHL), a consequence of a progressive degeneration of the primary auditory neurons (ANs), the afferent neurons of the cochlea. These ANs ...
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6
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TERMINÉ
European Consortium for Communicating Stem Cell Research (EuroStemCell)
Date du début: 1 mars 2010, Date de fin: 28 févr. 2015,
The European Consortium for Communicating Stem Cell Research, EUROSTEMCELL, brings together the major current FP6 and FP7 stem cell projects, the European Clinical Research Infrastructure Network, and four internationally recognized European stem cell centres to develop a comprehensive, coordinated platform for collation, dissemination and archiving of information on stem cell biology and regenera ...
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11
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TERMINÉ
Activation of vasculature associated stem cells and muscle stem cells for the repair and maintenance of muscle tissue (Endostem)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2014,
We propose to develop new strategies to mobilize skeletal muscle tissue-associated stem cells as a tool for efficient tissue repair. This will be combined with exploring novel approaches that limit tissue damage, and will focus on agents that modify muscle and muscle vasculature progenitor cells. These molecules include nitric oxide associated with non-steroidal anti-inflammatory drugs, HMGB1, Cri ...
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22
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TERMINÉ
Optimization of stem cell therapy for clinical trials of degenerative skin and muscle diseases (OptiStem)
Date du début: 1 janv. 2009, Date de fin: 31 déc. 2013,
This proposal aims to develop and implement efficacy of clinical trials with adult, tissue stem cells for degenerative diseases of epithelia and skeletal muscle. Extraordinary progress in the understanding of several key features of stem cells has been rapidly translated into novel cell therapy protocols that have yielded positive results in pre-clinical models of genetic and acquired diseases and ...
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20
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TERMINÉ
Angiogenesis-inducing Bioactive and Bioresponsive Scaffolds in Tissue Enginering (AngioScaff)
Date du début: 1 déc. 2008, Date de fin: 30 nov. 2012,
Angiogenesis underlies almost all biological processes of morphogenesis, including those in tissue repair and regeneration. Physiological angiogenesis is controlled by a complex interplay between cells and their environment: the extracellular matrix (ECM) provides signaling via numerous ECM adhesion molecules and growth factors bound to ECM polysaccharide components; and cells locally degrade and ...
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33
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TERMINÉ
Promotion of plasticity as a treatment for neurodegenerative conditions (PLASTICISE)
Date du début: 1 déc. 2008, Date de fin: 30 nov. 2012,
"Neurodegenerative diseases all cause damage to the circuitry of the nervous system, with loss of connections, axons and neurons. The loss can be gradual, as in Alzheimer’s disease, rapid as in stroke, or intermediate as in the delayed neuronal loss after stroke. Following damage, the nervous system is able partially to compensate through the formation of alternative connections and pathways, a pr ...
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16
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TERMINÉ
Spinal locomotor circuits: organization and repair after injury (SPINAL CORD REPAIR)
Date du début: 1 janv. 2008, Date de fin: 30 juin 2011,
"Neural circuits in the spinal cord, called central pattern generators (CPGs), can produce locomotor movements. The locomotor activity pattern is the result of the circuit design and the interplay between the firing properties of the CPG constituent neurons and their synaptic interactions. Spinal cord injury impairs the function of the locomotor circuitry and results in paralysis. An understanding ...
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