6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Bioactivated hierarchical hydrogels as zonal implants for articular cartilage regeneration (HYDROZONES)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
Degeneration of cartilage is a major cause of chronic pain, lost mobility and reduced quality of life for millions of European citizens. From a clinical point of view treatment to achieve cartilage regeneration (hyaline) and not only repair (fibrous) remains a great challenge. No clinical therapy is available that leads to healing of cartilage defects.Current cartilage implants cannot establish th ...
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18
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TERMINÉ
RADical reduction of OXidative stress in cardiovascular diseases (RADOX)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
Cardiovascular disease (CVD) constitutes a major and increasing health burden in developed countries. The prediction is that the prevalence of these conditions will increase by ~60% over the next 20 years. Therefore, the development of novel treatments for patients with CVD becomes more and more urgent. Oxidative stress is an important molecular contributor to the pathogenesis of CVD. However, ox ...
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10
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TERMINÉ
Transposon-based, targeted ex vivo gene therapy to treat age-related macular degeneration (AMD) (TARGETAMD)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
Age-related Macular Degeneration (AMD), a neurodegenerative disease of the retina, is a major cause of blindness in elderly people. Due to the aging population, AMD has been referred to as a “time bomb” in society. In the exudative form of AMD, high levels of vascular endothelial cell growth factor (VEGF) and low levels of pigment-epithelial derived factor (PEDF), an inhibitor of vascularization a ...
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16
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TERMINÉ
Selection and improving of fit-for-purpose sampling procedures for specific foods and risks (BASELINE)
Date du début: 1 août 2009, Date de fin: 30 nov. 2013,
"Food Safety Objectives (FSO) and Performance Objectives (PO) are new criteria complementing the existing concepts of microbiological criteria and MRL for many chemical contaminants. However, to achieve these objectives it is critically important a harmonisation of food safety control procedures.BASELINE project intends to obtain the following objectives: 1) To review the sampling schemes currentl ...
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20
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TERMINÉ
European Network for Cell Imaging and Tracking Expertise (ENCITE)
Date du début: 1 juin 2008, Date de fin: 30 nov. 2012,
"Cell therapy can be defined as the transplantation of living cells for the treatment of medical disorders. Three different principles underlie the increasing interest in cell therapy. 1. Transplanted cells used as an “active drug” 2. Transplanted cells used to replace damaged and degenerated tissue. 3. Cells used as a drug delivery vehicle. Promising results have been obtained in pre-clinical and ...
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30
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TERMINÉ
Therapy after heart infarct: prevention of reperfusion injury and repair by stem cell transfer (Infarct Cell Therapy)
Date du début: 1 janv. 2009, Date de fin: 30 juin 2012,
A key problem in repair and functional regeneration following myocardial infarction is the inability of heart muscle tissue to regenerate itself and appropriate vascularization under conditions of increased strain caused by the reduced contractibility of the damaged heart. This frequently leads to continuous loss of functional cells, further increase of the infarct area and finally complete loss o ...
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