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Solid state NMR study of small multidrug resistance proteins (SMRSSNMR)

Date du début: 1 sept. 2008, Date de fin: 31 août 2010,

"Small multidrug resistance proteins (SMR) were proven to be one of the responsible factors for drug resistance of bacteria, which represents an actual and serious problem in the therapy of several infectious diseases. Despite of the recent extensive biochemical investigations of SMR proteins the mechanism of substrate recognition and translocation is not yet clearly understood. The aim of the pro ...
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