6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Lysosomes as targets for cancer therapy (LYSOSOME)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
"Knowing that the lysosomes contain a powerful cocktail of hydrolases capable of digesting cells and entire tissues, it is obvious that the maintenance of lysosomal membrane integrity is of utmost importance for all cells, and especially for cancer cells with dramatically increased lysosomal activity. Yet, the mechanisms that regulate lysosomal membrane stability have remained obscure, largely due ...
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1
Participant partenaire
TERMINÉ
Health consequences of noise exposure from road traffic (QUIET)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
There is growing public concern about adverse effects of traffic noise on health, as research has found that traffic noise increases the risk for cardiovascular diseases. Noise is thought to act as a stressor and disturbs sleep. Though this potentially could increase the risk for other major diseases, noise effects on other than the cardiovascular diseases are virtually unexplored.The main objecti ...
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2
Participants partenaires
TERMINÉ
Epidemiological study to quantify risks for paediatric computerized tomography and to optimise doses (EPI-CT)
Date du début: 1 févr. 2011, Date de fin: 31 janv. 2017,
Diagnostic radiation represents an indispensable, sometimes life-saving, tool in modern medicine. However, the growing use of computerized tomography (CT) is a topic of concern in radiological protection, especially for children and adolescents. Children are generally more sensitive to the carcinogenic effects of ionizing radiation than adults. In addition, they have a longer life-span to express ...
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22
Participants partenaires
TERMINÉ
Consortium on Health and Ageing: Network of Cohorts in Europe and the United States (CHANCES)
Date du début: 1 févr. 2010, Date de fin: 31 janv. 2015,
CHANCES aims at combining and integrating on-going cohort studies in order to produce evidence on ageing-related health characteristics and determinants in Europe, and their socio-economic implications. 15 cohorts participate, covering populations from 18 EU Member States, 4 associate countries, and 3 additional countries. The combination of these different studies would lead to an integrated appr ...
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17
Participants partenaires
TERMINÉ
Collaborative Oncological Gene-environment Study (COGS)
Date du début: 1 mai 2009, Date de fin: 31 janv. 2014,
The overarching goal of COGS is to identify individuals with an increased risk of breast, ovary and prostate cancer. Furthermore, we will evaluate the effect of inherited genetic variation on tumour characteristics and clinical outcome. We will do this through quantifying the role of genetic and environmental/lifestyle risk in the largest data set ever generated. In all, we will include over 200,0 ...
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16
Participants partenaires
TERMINÉ
Prospective cohort studies of children with substantial medical diagnostic exposure (CHILD-MED-RAD)
Date du début: 1 sept. 2008, Date de fin: 30 nov. 2009,
The growing use of diagnostic X-rays and of high-dose techniques (CT, interventions) in children and adolescents is a topic of concern in radiological protection. Studies of other populations indicate that children are generally more sensitive to health effects of radiation than adults. In addition, children have a longer life-span to express any radiation-related health effect and, because of the ...
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