5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
The influence of environmental factors on antimicrobial activity of human intestinal defensins (Defensinactivity)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2018,
Human epithelia are permanently challenged by microorganisms. In the gut, the fraction of strict anaerobic bacteria increases from proximal to distal, reaching 99% of bacterial species in the colon. Moreover, microbial metabolism causes a reduction of the environment to a low redox potential of only –200 mV to –300 mV. Defensins, characterised by three intramolecular disulfide-bridges, are key eff ...
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2
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TERMINÉ
New Models for Preclinical Evaluation of Drug Efficacy in Common Solid Tumours (PREDECT)
Date du début: 1 févr. 2011, Date de fin: 30 avr. 2016,
Traditional preclinical discovery methods, particularly for target validation, poorly predict drug efficacy, causing a high attrition rate in costly late-stage clinical trials. The PREDECT consortium will focus on complex but transferable, next generation in vitro and in vivo models for breast, prostate and lung cancers. Models will be investigated for their improved potential to validate novel th ...
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23
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TERMINÉ
Prevention of Falls Network for Dissemination (ProFouND)
Date du début: 1 mars 2013, Date de fin: 29 févr. 2016,
Description
The Prevention of Falls Network for Dissemination (ProFouND) is a thematic network working with the European Innovation Partnership on Active and Healthy Ageing to bring about the dissemination and implementation of best practice in falls prevention across Europe. ProFouND comprises 21 partners from 12 countries, with associate m ...
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22
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TERMINÉ
Efficacy and Safety of Inhaled Budesonide in Very Preterm Infants at Risk for Bronchopulmonary Dysplasia (NEUROSIS)
Date du début: 1 mars 2009, Date de fin: 31 août 2015,
HYPOTHESIS: Early inhalation of Budesonide (BS) reduces the absolute risk of developing bronchopulmonary dysplasia (BPD) or death in preterm infants born between 23 and 27 weeks gestational age (GA) by 10%. PRIMARY OBJECTIVE: Survival without BPD at 36 weeks GA. SECONDARY OBJECTIVES: (1) neurodevelopment at a corrected age of 18-22 months; (2) adverse treatment effects; (3) mortality at 36 weeks G ...
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15
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TERMINÉ
FAll Repository for the design of Smart and sElf-adaptive Environments prolonging INdependent livinG (FARSEEING)
Date du début: 1 janv. 2012, Date de fin: 31 mars 2015,
Description
FARSEEING wants to provide an information basis for research and therapy development for fall prediction, prevention and support, by building the world’s largest fall repository. This database will facilitate the collection, analysis and processing of behavioural and physiological data related to falls, daily activity and physiol ...
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