3 projets européens trouvés
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TERMINÉ
Recruitment and activation of brown adipocytes as preventive and curative therapy for type 2 diabetes (DIABAT)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
"The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and diabetes due to last years re-discovery of functional BAT in adult humans by several of the members of the ...
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22
Participants partenaires
TERMINÉ
Bile acids targeting Retinoic Related Orphan Receptor gamma for the Treatment of Obesity associated Insulin Resistance and Type 2 Diabetes (DIBAROR)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2013,
"Within the past three years as part of the ERC funding, we have performed extensive research to identify novel factors that might influence adipogenesis and thus control development of obesity and associated metabolic disorders. One of the factors we identified in a translational approach, was the transcription factor retinoic acid orphan receptor gamma (RORγ) which regulates fat cell formation i ...
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1
Participant partenaire
TERMINÉ
Lipid droplets as dynamic organelles of fat deposition and release: Translational research towards human disease (LipidomicNet)
Date du début: 1 mai 2008, Date de fin: 31 oct. 2012,
Lipids are central to the regulation and control of cellular processes by acting as basic building units for biomembranes, the platforms for the vast majority of cellular functions. Recent developments in lipid mass spectrometry have set the scene for a completely new way to understand the composition of membranes, cells and tissues in space and time by allowing the precise identification and quan ...
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