3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Mucus Permeating Nanoparticulate Drug Delivery Systems (ALEXANDER)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2016,
The objective of the ALEXANDER project is the identification of novel strategies (e.g., proteolytic enzyme strategy, thiomer strategy, zeta potential changing systems, SNEDDS strategy) and the optimization of existing strategies (e.g., disulfide breaking strategy and slippery surface strategy) for the efficient transport of nanocarriers through the mucus gel layer (e.g., intestinal, nasal, ocular, ...
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20
Participants partenaires
TERMINÉ
Managing Risks of Nanoparticles (MARINA)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
While there are standard procedures for product life cycle analysis, exposure, hazard, and risk assessment for traditional chemicals, is not yet clear how these procedures need to be modified to address all the novel properties of nanomaterials. There is a need to develop specific reference methods for all the main steps in managing the potential risk of ENM. The aim of MARINA is to develop such ...
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54
Participants partenaires
TERMINÉ
Profiling the toxicity of new drugs: a non animal-based approach integrating toxicodynamics and biokinetics (Predict-IV)
Date du début: 1 mai 2008, Date de fin: 31 oct. 2013,
The overall aim of Predict-IV is to develop strategies to improve the assessment of drug safety in the early stage of development and late discovery phase, by an intelligent combination of non animal-based test systems, cell biology, mechanistic toxicology and in-silico modelling, in a rapid and cost effective manner. A better prediction of the safety of an investigational compound in early develo ...
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