3 projets européens trouvés
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TERMINÉ
Vascular Endothelial interactionS and SpEciaLization (Vessel)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
The vascular network plays essential roles in animal biology. Local disruption or impaired function of the vascular network is known to cause various pathological conditions, such as ischemic heart disease and stroke. The angiogenic growth of blood vessels is critically required during development, growth and regeneration, but it can also promote the growth of cancer cells and contribute to diabet ...
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9
Participants partenaires
TERMINÉ
Small Artery Remodelling (SmArt)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,
Cardiovascular diseases are the leading cause of death and disability in the European population and represent a great burden of suffering and costs. Their complex etiology originates from different pathological stimuli and involves different cell types, resident in the vascular wall or infiltrating from the blood. The adaptation of the vasculature to physiological and pathophysiological forces de ...
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6
Participants partenaires
TERMINÉ
An integrated concept of tumor metastasis: implications for therapy (TuMIC)
Date du début: 1 avr. 2008, Date de fin: 31 mars 2012,
From many perspectives our concept of the process of metastasis is inadequate and needs to be revised. In particular, the potential impact of recent ideas about the cellular basis of tumor growth (cancer stem cells) and the establishment by remote tumors of special permissive microenvironments in target organs prior to metastasis (metastatic niches) remains to be explored. In the TuMIC project we ...
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