3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Linking perturbed maternal environment during periconceptional development, due to diabetes, obesity or assisted reproductive technologies, and altered health during ageing (EpiHealth)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,
Scientific evidence clearly indicates that ageing and health in adult life is programmed by genetic and epigenetic mechanisms early in life. Developmental plasticity in response to the environment, including nutrient availability, of mammalian embryos indicates the capacity for newly emerging embryonic and extraembryonic cell lineages to initiate compensatory responses which may attune nutrient de ...
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7
Participants partenaires
TERMINÉ
Embryonic Stem cell-based Novel Alternative Testing Strategies (ESNATS)
Date du début: 1 avr. 2008, Date de fin: 30 sept. 2013,
"ESNATS aims at developing a novel toxicity test platform based on embryonic stem cells (ESC), especially human ESC (hESC), to accelerate drug development, reduce R&D costs and propose a powerful alternative to animal tests (3 Rs). ESNATS will address current drug-testing shortcomings: - testing takes place late in the development cycle - animal test systems bear the risk of non-prediction due to ...
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34
Participants partenaires
TERMINÉ
Systems biology approaches to understand cell pluripotency Acronym: PluriSys (PluriSys)
Date du début: 1 janv. 2009, Date de fin: 30 juin 2012,
The PluriSys project is aimed at increasing the fundamental knowledge of basic biological processes of cell pluripotency and differentiation by generating new holistic data on gene expression and epigenetic modifications associated with cell pluripotency. The project integrates the multidisciplinary excellence in Europe in cell biology, molecular biology and bioinformatics. It also builds on earli ...
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