Plus de 40 projets européens trouvés
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TERMINÉ
ORTHOpedic randomized clinical trial with expanded bone marrow MSC and bioceramics versus autograft in long bone nonUNIONs (ORTHOUNION)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
Current orthopaedic treatments permit spontaneous bone regeneration to unite and heal 90% bone injuries. Non-union associates pain and disability, often requiring biological enhancement. Regenerative medicine research suggests to the general public that alternative treatments based on advanced therapy medicinal products (ATMP) are already available. However, early clinical trials only explore its ...
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13
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TERMINÉ
Penumbral Rescue by Normobaric O=O Administration in Patients With Ischaemic Stroke and Target Mismatch ProFile: A Phase II Proof-of-Concept Trial (PROOF)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
Ischemic stroke (IS), caused by occlusion of arteries that supply blood to the brain, remains a leading cause of mortality and morbidity in the world. Disruption of blood and oxygen supply to the brain leads to neuronal death in the ischemic core within minutes. The hypoperfused tissue surrounding the ischemic core, the penumbra, is at high risk for infarction over time but still salvageable. Neur ...
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13
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TERMINÉ
Combatting Bacterial Resistance in Europe - Molecules against Gram Negative Infections (COMBACTE-MAGNET)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2021,
Antimicrobial resistance (AMR) is a major global public health threat, and most troublesome is the rapid emergence and dissemination of multidrug resistant (MDR) Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa. There is an unmet medical need to prevent P. aeruginosa infection in critically ill patients and to develop new antibiotics for infections caused by Gram-negative bacte ...
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44
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TERMINÉ
Marine Renewable Infrastructure Network for Enhancing Technologies 2 (MARINET2)
Date du début: 1 janv. 2017, Date de fin: 30 juin 2021,
Integrating activities planned under MaRINET 2 build upon the achievements of the advanced community created in MaRINET FP7. MaRINET 2 will ensure the continued integration and enhancement of all leading European research infrastructure and facilities specialising in research, development and testing of offshore renewable energy systems including electrical sub systems and grid integration through ...
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39
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TERMINÉ
Soil Care for profitable and sustainable crop production in Europe (SOILCARE)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,
European crop production is to remain competitive while reducing environmental impacts, requiring development and uptake of effective soil improvingcropping systems. The overall aim of SOILCARE is to identify and evaluate promising soil-improving cropping systems and agronomictechniques increasing profitability and sustainability across scales in Europe. A trans-disciplinary approach will be used ...
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29
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TERMINÉ
Linking genetic resources, genomes and phenotypes of Solanaceous crops (G2P-SOL)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,
G2P-SOL is a research alliance bringing together the major European and International repositories of germplasm with public and private institutions active in genomics, phenotyping and breeding in the four major Solanaceous crops: potato, tomato, pepper and eggplant. These four crops constitute 66% of the value of European horticultural production, and over 65,000 accessions are available within t ...
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20
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TERMINÉ
Joining up Users for Maximising the Profile, the Innovation and the Necessary Globalisation of JIVE (JUMPING JIVE)
Date du début: 1 déc. 2016, Date de fin: 31 janv. 2021,
“Joining up Users for Maximising the Profile, the Innovation and the Necessary Globalisation of JIVE” (JUMPING JIVE) aims to prepare and position European Very Long Baseline Interferometry (VLBI) for the SKA era, and to secure the role of JIV-ERIC in the European and global landscape of Research Infrastructures. On a European scale, the proposed activities will raise the profile of JIVE among scie ...
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13
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TERMINÉ
REgenerative therapy of intervertebral disc: a double blind phase 2b trial of intradiscal injection of mesenchymal stromal cells in degenerative disc disease of the lomber SPINE unresponsive to conventional therapy (RESPINE)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
...s. In addition, MRI T2 relaxation measurements demonstrated a significant improvement. To develop the world’s first rigorously proven, effective treatment of DDD, RESPINE aims to assess, via a multicentre, randomized, controlled, phase 2b clinical trial including 112 patients with DDD, the efficacy of an allogenic intervertebral mesenchymal stem cell (MSC)-based therapy. This innovative therapy ai ...
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18
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TERMINÉ
SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine (SPIDIA4P)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients’ samples with post c ...
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21
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TERMINÉ
Optical Infrared Coordination Network for Astronomy (OPTICON)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Europe has become a global leader in optical-near infrared astronomy through excellence in space and ground-based experimental and theoretical research. While the major infrastructures are delivered through major national and multi-national agencies (ESO, ESA) their continuing scientific competitiveness requires a strong community of scientists and technologists distributed across Europe’s nations ...
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34
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TERMINÉ
Towards enduring mouse resources and services advancing research into human health and disease (INFRAFRONTIER2020)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is st ...
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33
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TERMINÉ
Paediatric Clinical Research Infrastructure Network (PedCRIN)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Children’s health is a major societal challenge for Europe and the world, requiring development of paediatric medicines and treatments strategies based on evidence derived from clinical trials demonstrating efficacy and safety in infants and children, rather than on uncritical extrapolation from adult data (over 50 % of the medicines used for children had not been tested in this specific age group ...
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16
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TERMINÉ
European Research and Innovation Centre of Excellence in ChiNA (ERICENA)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
...Europe aims to foster international cooperation and strengthen its STI presence in China due to its growing importance and STI opportunities for European actors. ERICENA (European Research Innovation Centre of Excellence in China), a 48 month initiative implemented by 8 European and 5 Chinese partners, proposes to set up a Centre and its networks in China to promote European STI interests in China ...
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13
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TERMINÉ
European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates (EHVA)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
...scientists and clinicians; b) the most innovative technologies to profile immune response and virus reservoir; c) the access to large cohort studies bringing together top European clinical scientists/centres in the fields of prophylactic and therapeutic vaccines, d) the access to a panel of experimental HIV vaccines under clinical development that will be used as benchmark, and e) the liaison to a ...
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43
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TERMINÉ
Analytical and Characterisation Excellence in nanomaterial risk assessment: A tiered approach (ACEnano)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,
An increasing number of nanomaterials (NMs) are entering the market in every day products spanning from health care and leisure to electronics, cosmetics and foodstuff. Nanotechnology is a truly enabling technology, with unlimited potential for innovation. However, the novelty in properties and forms of NMs makes the development of a well-founded and robust legislative framework to ensure safe dev ...
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27
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TERMINÉ
Applied Public-Private Research enabling OsteoArthritis Clinical Headway (APPROACH)
Date du début: 1 juin 2015, Date de fin: 30 nov. 2020,
The problem: finding the right patient for the right treatmentDespite a large and growing disease burden in osteoarthritis (OA), many pharmaceutical companies have de-emphasized or even abandoned OA drug development due to perceived hurdles. Crucial in this is the lack of appropriate outcome measures that can robustly identify patient benefit from a specific therapy. The lack of specific and sensi ...
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25
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TERMINÉ
Bridging Innovative Downstream Earth Observation and Copernicus enabled Services for Integrated maritime environment, surveillance and security (MARINE-EO)
Date du début: 1 janv. 2017, Date de fin: 30 nov. 2020,
Maritime “Awareness” is currently a top priority for Europe. “Awareness” sought either in regards of maritime security, border control against irregular immigration and safety of navigation while at the same time “awareness” sought in regards of the marine environment and climate change. “Awareness” is sought both for sea-basins of traditional interest like the Mediterranean and the Atlantic as we ...
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10
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TERMINÉ
SeaDataCloud - Further developing the pan-European infrastructure for marine and ocean data management (SeaDataCloud)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
The SeaDataNet pan-European infrastructure has been developed by NODCs and major research institutes from 34 countries. Over 100 marine data centres are connected and provide discovery and access to data resources for all European researchers. Moreover, SeaDataNet is a key infrastructure driving several portals of the European Marine Observation and Data network (EMODnet), initiated by EU DG-MARE ...
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57
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TERMINÉ
Advanced Prediction in Polar regions and beyond: Modelling, observing system design and LInkages associated with ArctiC ClimATE change (APPLICATE)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
...n the Arctic and beyond. APPLICATE will address this challenge and develop enhanced predictive capacity by bringing together scientists from academia, research institutions and operational prediction centres, including experts in weather and climate prediction and forecast dissemination. APPLICATE will develop a comprehensive framework for observationally constraining and assessing weather and cli ...
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16
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TERMINÉ
Xylella Fastidiosa Active Containment Through a multidisciplinary-Oriented Research Strategy (XF-ACTORS)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
XF-ACTORS aims to establish a multidisciplinary research program to answer the urgent need to improve prevention, early detection and control of Xylella fastidiosa (Xf). Recently, Xf was introduced into Italy, where it is causing severe damage to olive crops, and in France, where so far it is limited to ornamental plants and some landscape trees. The overall goal of the research program is to asse ...
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32
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TERMINÉ
AQUAculture infrastructures for EXCELlence in European fish research towards 2020 (AQUAEXCEL2020)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,
AQUAEXCEL2020 aims to integrate top class European aquaculture research facilities of very diverse nature, covering all relevant scientific fields for research and innovation in aquaculture, from genetics to technology through pathology, physiology and nutrition. It will put in place a user-friendly one-stop access to high-quality services and resources from 39 installations covering both establis ...
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22
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TERMINÉ
Alternative models and robust decision-making for future forest management (ALTERFOR)
Date du début: 1 avr. 2016, Date de fin: 30 sept. 2020,
European forests are expected to provide a broad range of ecosystem services (ES). This capacity is however threatened by the uncertainties of climate change, the complex dynamics of evolving global markets and the pressures for increased use of bioenergy. Such challenges cannot be effectively addressed with an uncritical regional or national commitment to traditional forest management models (FMM ...
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21
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TERMINÉ
DAFNE: Use of a Decision-Analytic Framework to explore the water-energy-food NExus in complex and trans-boundary water resources systems of fast growing developing countries. (DAFNE)
Date du début: 1 sept. 2016, Date de fin: 31 août 2020,
Global trends in population growth and rising economic prosperity will increase the demand for energy, food and water, with more severe impact in fast-growing economies, such as in several African countries. The constraints on water, energy, and food could well hamper economic development, lead to social and geopolitical tensions, and cause lasting environmental damage. DAFNE advocates an integrat ...
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13
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TERMINÉ
Advanced solutions for assuring the overall authenticity and quality of olive oil (OLEUM)
Date du début: 1 sept. 2016, Date de fin: 31 août 2020,
The OLEUM project will generate innovative, more effective and harmonized analytical solutions to detect and fight the most common and emerging frauds and to verify the overall quality of olive oils (OOs). By a core group of 20 partners from 15 countries OLEUM will undertake RESEARCH ACTIVITIES based on the development of IMPROVED and NEW ANALYTICAL METHODS by targeted and omics approaches with th ...
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24
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TERMINÉ
A Citizen Observatory and Innovation Marketplace for Land Use and Land Cover Monitoring (LANDSENSE)
Date du début: 1 sept. 2016, Date de fin: 31 août 2020,
Currently within the EU’s Earth Observation (EO) monitoring framework, there is a need for low-cost methods for acquiring high quality in-situ data to create accurate and well-validated environmental monitoring products. The aim of the LandSense project is to build a far reaching citizen observatory for Land Use and Land Cover (LULC) monitoring that will also function as a technology innovation ma ...
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17
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TERMINÉ
REPAiR - REsource Management in Peri-urban AReas: Going Beyond Urban Metabolism (REPAiR)
Date du début: 1 sept. 2016, Date de fin: 31 août 2020,
A shift towards a more circular economy is crucial to achieve more sustainable and inclusive growth. Our objective is to provide local and regional authorities with an innovative transdisciplinary open source geodesign decision support environment (GDSE) developed and implemented in living labs in six metropolitan areas. The GDSE allows creating integrated, place-based eco-innovative spatial devel ...
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18
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TERMINÉ
Adaptive Management of Barriers in European Rivers (AMBER)
Date du début: 1 juin 2016, Date de fin: 31 mai 2020,
Rivers rank among some of the most threatened ecosystems in the world, and are the focus of costly restoration programmes that cost billions to taxpayers. Much of Europe depends on water from rivers for drinking, food production, and the generation of hydropower, which is essential for meeting the EU renewable energy target. Yet only half the EU surface waters have met the WFD’s 2015 target of goo ...
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21
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TERMINÉ
Next Generation GEOSS for Innovation Business (NextGEOSS)
Date du début: 1 déc. 2016, Date de fin: 31 mai 2020,
... charge of interconnecting the heterogeneous and distributed capacities contributing to GEOSS, NextGEOSS focuses on a fundamental change to facilitate the connectivity to the European and global data centres with new discovery and processing methods. It will leverage Web and Cloud technologies, offering seamless and user-friendly access to all the relevant data repositories, as well as providing e ...
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27
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TERMINÉ
Moving Towards Adaptive Governance in Complexity: Informing Nexus Security (MAGIC)
Date du début: 1 juin 2016, Date de fin: 31 mai 2020,
MAGIC is a proposal coordinated by the Institute of Environmental Science and Technology (ICTA) of the Autonomous University of Barcelona (UAB) in collaboration with partners which have a proven and track record in their respective fields of competence.Our objective is to open the path towards a new way of managing the Nexus in which researchers and decision makers work together in the search for ...
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9
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TERMINÉ
Conservative iron chelation as a disease-modifying strategy in Parkinson’s disease: a multicentric, parallel-group, placebo-controlled, randomized clinical trial of deferiprone (FAIR-PARK-II)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
... moderate-dose DFP (30 mg/kg/day) slows the progression of handicap in de novo PD patients while not affecting systemic parameters. The 9-month, parallel-group, randomized, placebo-controlled, multicentre trial will be followed by a 1-month wash-out period. The primary efficacy criterion will be the change in motor and non-motor handicap scores on the Total Movement Disorders Society Unified Parki ...
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17
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TERMINÉ
A multi-center randomized, placebo-controlled trial of mirabegron, a new beta3-adrenergic receptor agonist on left ventricular mass and diastolic function in patients with structural heart disease (BETA3_LVH)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Patients with cardiovascular risk factors, e.g. hypertension and obesity are at risk of developing heart failure with preserved ejection fraction (HFpEF), a highly prevalent disease in the elderly, mostly women population. There is currently no specific, defined treatment for HFpEF, beyond control of risk factors. Activation of cardiac and vascular Beta3-adrenergic receptors (B3AR) represents a ne ...
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15
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TERMINÉ
Low energy solution for drinking water production by a REvival of ElectroDialysis systems (REvivED water)
Date du début: 1 mai 2016, Date de fin: 30 avr. 2020,
The REvivED water project will establish electrodialysis (ED) as the new standard providing a source of safe, affordable, and cost-competitive drinking water, using less than half the energy required by state-of-the-art Reverse Osmosis (RO) plants.The innovations of the project constitute a technology platform with a very wide field of potential applications. All components and systems have reache ...
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10
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TERMINÉ
European Research Infrastructure supporting Smart Grid Systems Technology Development, Validation and Roll Out (ERIGrid)
Date du début: 1 nov. 2015, Date de fin: 30 avr. 2020,
...rts the technology development as well as the roll out of Smart Grid solutions and concepts in Europe. It tackles a holistic, cyber-physical systems based approach by integrating 18 European research centres and institutions with outstanding research infrastructures and jointly develops common methods, concepts, and procedures. ERIGrid also integrates and enhances the necessary research services f ...
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19
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TERMINÉ
Interactive Soil Quality Assessment in Europe and China for Agricultural Productivity and Environmental Resilience (iSQAPER)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Knowledge regarding the complex interplay between agricultural land use and management and soil quality and function is fragmented and incomplete, in particular with regard to underlying principles and regulating mechanisms. The main aim of iSQAPER is to develop an interactive soil quality assessment tool (SQAPP) for agricultural land users that integrates newly derived process understanding and a ...
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25
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TERMINÉ
Social Innovation in Marginalised Rural Areas (SIMRA)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2020,
SIMRA seeks to advance understanding of social innovation (SI) and innovative governance in agriculture, forestry and rural development (RD), and how to boost them, particularly in marginalised rural areas across Europe, with a focus on the Mediterranean region (including non-EU) where there is limited evidence of outcomes and supporting conditions. These objectives will be achieved by: 1. Develop ...
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26
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TERMINÉ
A holistic multi-actor approach towards the design of new tomato varieties and management practices to improve yield and quality in the face of climate change (TomGEM)
Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,
The world demographic growth and global climate change are major challenges for human society,hence the need to design new strategies for maintaining high crop yield in unprecedented environmental conditions.The objective of TomGEM is to design new strategies aiming to maintain high yields of fruit and vegetables at harsh temperature conditions, using tomato as a reference fleshy fruit crop.As yie ...
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18
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TERMINÉ
Standardization and Development of Assays for Assessment of Influenza Vaccines Correlates of Protection (FLUCOP)
Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,
Background: Influenza viruses cause annual epidemic and occasional pandemics, both of which induce significant morbidity and mortality. Influenza infections affect all age groups but children and adults over the age of 65 are at most risk of developing severe disease.Vaccination is the most effective approach to reduce the impact of annual influenza outbreaks and potential pandemics, however, the ...
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26
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TERMINÉ
European Nuclear Science and Application Research 2 (ENSAR2)
Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,
ENSAR2 is the integrating activity for European nuclear scientists who are performing research in three of the major subfields defined by NuPECC: Nuclear Structure and Dynamics, Nuclear Astrophysics and Nuclear Physics Tools and Applications. It proposes an optimised ensemble of Networking (NAs), Joint Research (JRAs) and Transnational Access Activities (TAs), which will ensure qualitative and qua ...
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31
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TERMINÉ
European Gram Negative Antibacterial Engine (ENABLE)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,
The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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42
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TERMINÉ
InvisiblesPlus
Date du début: 1 févr. 2016, Date de fin: 31 janv. 2020,
NEUTRINOS (Ns) and DARK MATTER (DM) are the most abundant particles in the universe. Their couplings to ordinary matter are so tenuous that they remained undiscovered -invisible- until very recently. N masses and DM constitute the first evidence ever of physics beyond the Standard Model of particle physics. The path to build the New Standard Model must confront the fundamental nature of the partic ...
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