4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Systems microscopy – a key enabling methodology for next-generation systems biology (Systems Microscopy)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
Biological processes occur in space and time, but current experimental methods for systems biology are limited in their ability to resolve this spatiotemporal complexity of life. In addition, traditional “omics” methods often suffer from limited sensitivity and need to average over populations of cells at the expense of cell to cell variation. Next-generation systems biology therefore requires met ...
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11
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TERMINÉ
Recognition and Cleavage of Biological Phosphates – Molecular Recognition, Mechanism and Biomedical Applications (PhosChemRec)
Date du début: 1 juil. 2010, Date de fin: 30 juin 2014,
Chemical Biology is a new, supradisciplinary field that unites the classically separate disciplines of Chemistry and Biology. This network is centred around understanding the central biological process of phosphate transfer and combines leading experts in synthetic chemistry, enzyme model building, kinetic analysis, protein chemistry and directed evolution in a concerted effort to gain a quantitat ...
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10
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TERMINÉ
Normalisation of immune reactivity in old age – from basic mechanisms to clinical application (TOLERAGE)
Date du début: 1 avr. 2008, Date de fin: 30 sept. 2012,
"When restoration of the immune response in older age is the target of basic and clinical research, boosting innate and adaptive immunity, e.g. by more efficient vaccination strategies, is the general approach. However, TOLERAGE has a fundamentally different focus, i.e. restoring the age-dependent decline of auto-tolerance that underlies the development of the paradigmatic age-associated diseases ...
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10
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TERMINÉ
Understanding and fighting metastasis via dissection of the Core Invasive Machinery (MetaFight)
Date du début: 1 janv. 2008, Date de fin: 31 déc. 2010,
The co-operative Metafight project will perform functional studies to understand the dissemination and outgrowth of metastasis through systematic analysis of the Core Invasive Machinery contained within integrin-mediated ECM attachment structure. It includes a large and discretely localised intracellular signalling network which drives migration and invasion. Our strategy is based on the hypothesi ...
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