3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Model-based preclinical development of anti-tuberculosis drug combinations (PREDICT-TB)
Date du début: 1 mai 2012, Date de fin: 30 oct. 2017,
Drug development in TB requires new integrated methods to transition the novel combination regimens needed to shorten first-line therapy and combat multi-drug resistance. Although new agents are emerging, the path to registration of such regimens remains uncertain while capacity for pivotal trials is limited. Selection and optimization of drug combinations for development depends on preclinical sy ...
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23
Participants partenaires
TERMINÉ
Discovery and preclinical development of new generation tuberculosis vaccines (NEWTBVAC)
Date du début: 1 janv. 2010, Date de fin: 28 févr. 2014,
"With 14.4 million prevalent cases and 1.7 million deaths tuberculosis (TB) remains one of the most serious infectious diseases to date. An estimated 2 billion people are believed to be infected with Mycobacterium tuberculosis and at risk of developing disease. Multi- and extensively drug resistant strains are increasingly appearing in many parts of the world, including Europe. While with current ...
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39
Participants partenaires
TERMINÉ
European Network of Vaccine Development and Research (TRANSVAC)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,
"The TRANSVAC infrastructure will accelerate the pharmaceutical and clinical development of promising vaccine candidates by bringing the gap between academic research and clinical trials through carefully managing the advancement of promising vaccine candidates from preclinical animal models to early proof-of-principle studies in humans. Although expertise already exists within Europe spanning dif ...
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