6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Nose to Brain Delivery of NG-101 via the Olfactory Region for the Regenerative Treatment of Multiple Sclerosis Using Novel Multi-functional Biomaterials Combined with a Medical Device (N2B-patch)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The overall aim of N2B-patch is the development of a new innovative N2B drug delivery technology based on the synthesis of a biomaterial-based innovative galenic formulation that will be applied with the aid of a novel medical device equipped with a container closure system (CCS) as a hydrogel patch to the nasal olfactory region for the chronic treatment of MS. The galenic formulation will consist ...
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11
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TERMINÉ
Diabetes Reversing Implants with enhanced Viability and long-term Efficacy (DRIVE)
Date du début: 1 juin 2015, Date de fin: 31 mai 2019,
Diabetes mellitus is a chronic disease characterised by high blood glucose due to inadequate insulin production and/or insulin resistance which affects 382 million people worldwide. Pancreatic islet transplantation is an extremely promising cure for insulin-sensitive diabetes mellitus (ISDM), but side effects of lifelong systemic immunosuppressive therapy, short supply of donor islets and their po ...
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14
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TERMINÉ
Novel combination of biopolymers and manufacturing technologies for production of a peripheral nerve implant containing an internal aligned channels array (NEURIMP)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,
"Peripheral nerves are basic communication structures guiding motor and sensitive information from CNS to effector or receptor units. Severe nerve injuries include axon bundles section and Schawnn cells destruction, which results in loss of motion control and sensorial perception. After the lesion, cells present in damaged nerves activate spontaneously self-regeneration programs that might facilit ...
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8
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TERMINÉ
Advanced Materials for Cardiac Regeneration (AMCARE) (AMCARE)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,
The Advanced Materials for Cardiac Regeneration (AMCARE) consortium aims to establish a translational research program to develop truly restorative therapies for acute myocardial infarction repair (MI) by optimising cardiac progenitor cell (CPC) therapy using smart biomaterials and advanced drug delivery, and coupling these therapeutics with minimally-invasive surgical devices. Two distinct biomat ...
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10
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TERMINÉ
Local Immunomodulation around implants by innovative auxiliary hydrogel-based systems encapsulating autologous and phenotype controlled macrophages (IMMODGEL)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
IMMODGEL aims to identify adverse immune reactions to dental and larynx titanium implants and to develop a novel therapeutic strategy to significantly decrease the implant and medical device failure caused by these reactions via design of an innovative immunomodulatory system. The system will be designed to be fixed to an implant via an adhesive polyelectrolyte multilayer and control the immune re ...
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9
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TERMINÉ
Implantable Organic Nano-Electronics (iONE-FP7)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2015,
The vision of iONE-FP7 is to exploit for the first time flexible organic electronics for the development and testing of Active Multifunctional Implantable Devices (AMIDs) to treat Spinal Cord Injury (SCI). The devices will (a) have long-term stability associated to high biocompatibility and safety, (b) have reduced risk of a host versus graft immune response, (c) mimic the local microenvironment f ...
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