3 projets européens trouvés
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TERMINÉ
Tissue engineering of the right heart outflow tract by a biofunctionalized bioresorbable polymeric valved tube (TEH-TUBE)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,
Approximately 42% of infants’ mortality in the world is related to congenital heart defects (prevalence: 8-12/1000 births). Over 1/3 require the reconstruction of the right ventricular outflow tract (RVOT) by surgical procedures which currently use inert materials without any growth potential. Consequently, multiple reoperations are often required, with their attendant high risk of mortality and m ...
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7
Participants partenaires
TERMINÉ
The effect of intracoronary reinfusion of bone marrow-derived mononuclear cells (BM-MNC) on all-cause mortality in acute myocardial infarction (BAMI)
Date du début: 1 nov. 2011, Date de fin: 31 oct. 2017,
Although the long term prognosis of patients suffering acute myocardial infarction (AMI) has improved since the introduction of reperfusion therapies and primary angioplasty, the 1 year mortality of patients with AMI and resultant left ventricular systolic dysfunction (LVSD) is still as high as 13%. A major reason for the high morbidity and mortality is that the heart has an inadequate regenerativ ...
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23
Participants partenaires
TERMINÉ
Advanced Materials for Cardiac Regeneration (AMCARE) (AMCARE)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,
The Advanced Materials for Cardiac Regeneration (AMCARE) consortium aims to establish a translational research program to develop truly restorative therapies for acute myocardial infarction repair (MI) by optimising cardiac progenitor cell (CPC) therapy using smart biomaterials and advanced drug delivery, and coupling these therapeutics with minimally-invasive surgical devices. Two distinct biomat ...
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