Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
The role of immune cells in Alzheimer's disease (IMMUNOALZHEIMER)
Date du début: 1 sept. 2016, Date de fin: 31 août 2021,
"Alzheimer’s disease is the most common form of dementia affecting more than 35 million people worldwide and its prevalence is projected to nearly double every 20 years with tremendous social and economical impact on the society. There is no cure for Alzheimer's disease and current drugs only temporarily improve disease symptoms. Alzheimer's disease is characterized by a progressive deterioration ...
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2
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TERMINÉ
IMPROVING PHOTOSYNTHETIC SOLAR ENERGY CONVERSION IN MICROALGAL CULTURES FOR THE PRODUCTION OF BIOFUELS AND HIGH VALUE PRODUCTS (SOLENALGAE)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,
Solar Energy is the most abundant renewable energy source available for our Planet. Light energy conversion into chemical energy by photosynthetic organisms is indeed the main conversion energy step, which originated high energy containing fossil deposits, now being depleted. By the way, plant or algae biomass may still be used to produce biofuels, as bio-ethanol, bio-diesel and bio-hydrogen. Micr ...
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3
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TERMINÉ
European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates (EHVA)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the Eur ...
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43
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TERMINÉ
Breast CAncer STratification: understanding the determinants of risk and prognosis of molecular subtypes (B-CAST)
Date du début: 1 sept. 2015, Date de fin: 31 août 2020,
...ex interplay of multiple lifestyle/environmental and genetic risk factors. Through the EU-funded COGS project, we have identified a large number of germline variants that influence the risk of breast cancer. In combination, these variants can identify women at wide ranges of genetic risk, even in the absence of family history of breast cancer. Given that breast cancer is not one disease, it is now ...
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13
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TERMINÉ
Scale-up of low-carbon footprint material recovery techniques in existing wastewater treatment plants (SMART-Plant)
Date du début: 1 juin 2016, Date de fin: 31 mai 2020,
SMART-Plant will scale-up in real environment eco-innovative and energy-efficient solutions to renovate existing wastewater treatment plants and close the circular value chain by applying low-carbon techniques to recover materials that are otherwise lost. 7+2 pilot systems will be optimized fore > 2 years in real environment in 5 municipal water treatment plants, inclunding also 2 post-processing ...
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27
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TERMINÉ
Structural and mechanistic insights into RING E3-mediated ubiquitination (RINGE3)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
...greatly expand our knowledge of RING E3-mediated ubiquitination and will foster strategies in exploiting E3s for therapeutic development, since deregulation of E3s underlies many diseases including cancers.
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1
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TERMINÉ
Development and application of Novel, Integrated Tools for monitoring and managing Catchments (INTCATCH)
Date du début: 1 juin 2016, Date de fin: 31 janv. 2020,
INTCATCH will instigate a paradigm shift in the monitoring and management of surface water quality that is fit for global waters in the period 2020-2050. INTCATCH will do this by developing efficient, user-friendly water monitoring strategies and systems based on innovative technologies that will provide real time data for important parameters, moving towards SMART Rivers. The business model will ...
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23
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TERMINÉ
Sonic Drilling coupled with Automated Mineralogy and chemistry On-Line-On-Mine-Real-Time (SOLSA)
Date du début: 1 févr. 2016, Date de fin: 31 janv. 2020,
"SOLSA is the first automated expert system for on-site cores analysis. With access to data on-line, great savings are expected on the number of drill holes, the accuracy of geo-models and economic evaluation of ore reserves. SOLSA responds perfectly to the need for "New sustainable exploration technologies and geo-models" of SC5-11d-2015. The objective is to “develop new or improved highly effici ...
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10
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TERMINÉ
REsources from URban BIo-waSte (RES URBIS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,
RES URBIS aims at making it possible to convert several types of urban bio-waste into valuable bio-based products, in an integrated single biowaste biorefinery and by using one main technology chain. This goal will be pursued through: - collection and analysis of data on urban bio-waste production and present management systems in four territorial clusters that have been selected in different cou ...
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22
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TERMINÉ
Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood (CANCER-ID)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,
Blood-based biomarkers such as Circulating Tumor Cells (CTCs), circulating free tumor DNA (cfDNA) and microRNAs (miRNAs) have the potential to improve the development of personalized medicines for cancer patients. This is of particular importance when biopsies of the primary tumor or metastases are not accessible (e.g. at early disease stages or in minimal residual disease) or possible and the ass ...
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34
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TERMINÉ
MRI and Ultrasound Robotic Assisted Biopsy (MURAB)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
The MURAB project has the ambition to revolutionise the way cancer screening and muscle diseases are researched for patients and has the potential to save lives by early detection and treatment.The project intends to create a new paradigm in which, the precision of great medical imaging modalities like MRI and Ultrasound are combined with the precision of robotics in order to target the right plac ...
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8
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TERMINÉ
Imaging the Force of Cancer (FORCE)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
Cancer is the second leading cause of mortality in EU member states with ~90% of all cancer deaths caused by metastatic spread. Despite its significance, measuring metastatic potential as well as potential indicators of therapy efficacy remain unmet clinical challenges. Recently, it has been demonstrated in vitro, that aggressive metastatic cells pull on their surroundings suggesting that metastat ...
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18
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TERMINÉ
Tackling secondhand tobacco smoke and e-cigarette emissions: exposure assessment, novel interventions, impact on lung diseases and economic burden in diverse European populations. The TackSHS Project. (TackSHS)
Date du début: 1 nov. 2015, Date de fin: 31 oct. 2019,
"Exposure to secondhand tobacco smoke (SHS) has been classified as a "Group 1" carcinogen (known human carcinogen) by the International Agency for Research on Cancer and has been shown to have adverse health effects on adults and children, including heart disease and respiratory disorders. Electronic cigarettes (e-cigarettes), the most common “electronic nicotine delivery system”, have irrupted i ...
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11
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TERMINÉ
The use of genetic profiling to guide prostate cancer targeted screening and cancer care (BARCODE)
Date du début: 1 oct. 2014, Date de fin: 30 sept. 2019,
"Prostate cancer is the commonest solid cancer in men in the European Community. There is evidence for genetic predisposition to the development of prostate cancer and our group has found the largest number of such genetic variants described to date worldwide. The next challenge is to harness these discoveries to advance the clinical care of populations and prostate cancer patients to improve scre ...
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1
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TERMINÉ
Molecularly guided trials with specific treatment strategies in patients with advanced newly molecular defined subtypes of colorectal cancer (MoTriColor) (MoTriColor)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,
Colorectal cancer (CRC) is increasingly being recognized as a heterogeneous disease with distinct molecular subtypes. These subtypes have different biological processes at the basis of their disease and consequently their prognosis and responses to therapy are also different.We have previously developed molecular diagnostic assays using a single platform on routine FFPE tumour biopsies. These assa ...
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12
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TERMINÉ
Encouraging Lifelong Learning for an Inclusive and Vibrant Europe (ENLIVEN)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2019,
The ENLIVEN research models how policy interventions in adult education markets can become more effective. Integrating state-of-the-art methodologies and theorisations (e.g. Case-Based Reasoning methodology in artificial intelligence, bounded agency in adult learning), it implements and evaluates an innovative Intelligent Decision Support System to provide a new and more scientific underpinning fo ...
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11
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TERMINÉ
Time-lapse understanding of the static and human scene and its lighting (SCENEUNDERLIGHT)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,
Europe has a strong position in the fast-growing photonics and lighting industry but has to face the fast technological changes and, most importantly, a demand for larger transfer from research to industrial innovation and application. With the introduction of Solid State Lighting (SSL) new targets of energy efficiency were set and smart lighting technology was boosted.SCENEUNDERLIGHT leverages th ...
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3
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TERMINÉ
Tumour Heterogeneity and Somatic Evolution of Unstable cancer genomes (THESEUS)
Date du début: 1 juin 2014, Date de fin: 31 mai 2019,
SummaryThe majority of metastastic solid tumours remain incurable. In-depth analysis of tumour genomes is revealing evidence for branched evolution and cancer subclonal spatial and temporal intratumour heterogeneity (ITH). Drivers of ITH such as chromosomal instability (CIN) are associated with drug resistance and poor clinical outcome. However, despite increasing knowledge of tumour diversity, th ...
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3
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TERMINÉ
Aging Lungs in European Cohorts (ALEC)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
This programme of work will advance the understanding of the combined effects of factors that cause poor lung function, respiratory disability and the development of COPD . This will be achieved by examination of determinants of lung growth and lung function decline within existing cohorts that cover the whole life course, and which have followed, in detail, the respiratory health status of over 2 ...
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15
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TERMINÉ
Advancing the European Multilingual Experience (ATHEME)
Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,
"The project Advancing The European Multilingual Experience (AThEME) takes an integrated approach towards the study of multilingualism in Europe by incorporating and combining linguistic, cognitive and sociological perspectives; by studying multilingualism in Europe at three different levels of societal magnitude, viz. the individual multilingual citizen, the multilingual group, and the multilingu ...
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18
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TERMINÉ
Perceptual Awareness in the Reorganizing Brain (Perceptual Awareness)
Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,
"The present project aims at casting light on the neural and cognitive reorganization of visual function following unilateral lesion at various levels of the central visual system such as optic tract, optic radiation, primary visual cortex, extrastriate visual areas. In the first part of the project we will employ behavioural as well as brain imaging methods to study the basic neural mechanisms of ...
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4
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TERMINÉ
Integrative Analysis of Gene Functions in Cellular and Animal Models of Pancreatic Cancer (CAM-PAC)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Cancers are genetic disease arising from the accumulation of multiple molecular alterations in affected cells. Large-scale genomic, transcriptomic and proteomic analyses have established comprehensive catalogues of molecules which are altered in their structure and/or abundance in malignant tumors as compared to healthy tissues. Far less developed are concepts and methods to integrate data from di ...
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18
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TERMINÉ
implementAtion anD OPeration of the gateway for healTh into BBMRI-ERIC (ADOPT BBMRI-ERIC)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2018,
...r ESFRI-projects "under implementation", reflecting the targets of the European Research Area (ERA). One of the challenges in the post-genomic era is the research on common complex diseases, such as cancer, diabetes and Alzheimer’s disease. Revealing these diseases will depend critically on the study of human biological samples and data from large numbers of patients and healthy individuals. The ...
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22
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TERMINÉ
EURO EWING Consortium – International Clinical Trials to Improve Survival from Ewing Sarcoma (EEC)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
Ewing Sarcomas (ES) are fatal, rare bone cancers particularly affecting young people. About 60% of patients achieve long term survival with current treatment but there has been no improvement in this proportion for 25 years. Treatment is unsuccessful because chemotherapy fails to prevent the development of, or to effectively treat established, metastases. In addition, of the 600 new cases of ES o ...
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21
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TERMINÉ
Development and Epilepsy - Strategies for Innovative Research to improve diagnosis, prevention and treatment in children with difficult to treat Epilepsy (DESIRE)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
DESIRE will focus on epileptogenic developmental disorders EDD, i.e. early onset epilepsies whose origin is closely related to developmental brain processes. A major cause of EDD are malformations of cortical development (MCD), either macroscopic or subtle. EDD are often manifested as epileptic encephalopathies (EE), i.e. conditions in which epileptic activity itself may contribute to severe cogni ...
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29
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TERMINÉ
Multimodal Scanning of Cultural Heritage Assets for their multilayered digitization and preventive conservation via spatiotemporal 4D Reconstruction and 3D Printing (Scan4Reco)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2018,
Scan4Reco will develop a novel portable, integrated and modular solution for customized and thus cost-effective, automatic digitization and analysis of cultural heritage objects (CHOs), even in situ. A multi-sensorial 3D scanning - facilitated by a mechanical arm – will collect multi-spectra data and then, a hierarchical approach for 3D reconstruction of CHOs will be applied, enabling multi-layere ...
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10
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TERMINÉ
EUBET
Date du début: 1 sept. 2016, Date de fin: 31 août 2018,
Bromangymnasiet in Hudiksvall is situated in a region of very high unemployment, among the young it is the highest percentage in the country (25 %). Our school has the task and mission to develop an intercultural teaching practice supported by inclusive, innovative methods and entrepreneurship to achieve a more entrepreneurial learning for the benefits of our students. For some years now, we have ...
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62
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TERMINÉ
Statistical multi-Omics UNDerstanding of Patient Samples (SOUND)
Date du début: 1 sept. 2015, Date de fin: 31 août 2018,
Bioinformatic analysis is the biggest bottleneck in many genomic medicine projects. Our objective is to enable researchers to dramatically increase statistically informed use of personal multi-omic data in medicine. Soon, multiple types of omic technologies will be applied to 100,000s of patient-derived samples, with the three-stage goal of better understanding disease biology, discovery of new in ...
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11
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TERMINÉ
MicroRNAs in the Pathogenesis, Treatment and Prevention of Epilepsy (EPIMIRNA)
Date du début: 1 sept. 2013, Date de fin: 31 août 2018,
Epilepsy is a major burden for patients and health systems worldwide. It is a common chronic neurological disorder affecting people of all ages, and the shortfall in existing treatments means that 30% of patients continue to suffer uncontrolled seizures. MicroRNAs (miRNA) are a recently-discovered, network-level layer of gene expression regulation that controls protein levels of entire signaling p ...
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19
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TERMINÉ
The 4th Geneva Convention’s Drafting History as the origin of the Responsibility to Protect (R2P) and Duty to Prevent (D2P). (REQUE 2)
Date du début: 1 sept. 2016, Date de fin: 31 août 2018,
The objective of this project is to uncover the source materials of current humanitarian norms (Responsibility to Protect and Duty to Prevent) within the first and most important tool of International Humanitarian Law – the 4th Geneva Convention for the Protection of Civilians (1949). Specifically, this project aims to generate a comprehensive historical and legal account of the drafting process a ...
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2
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TERMINÉ
iManageCancer - Empowering patients and strengthening self-management in cancer diseases (iManageCancer)
Date du début: 1 févr. 2015, Date de fin: 31 juil. 2018,
Chronic cancer treatment places new demands on patients and families to manage their own care. The iManageCancer project will support this challenge and provide a cancer disease self-management platform designed according to the specific needs of patient groups and focusing on the wellbeing of the cancer patient with special emphasis on psycho-emotional evaluation and self-motivated goals. The pla ...
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11
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TERMINÉ
Bridging Biobanking and Biomedical Research across Europe and Africa (B3Africa)
Date du début: 1 juil. 2015, Date de fin: 30 juin 2018,
B3Africa - Bridging Biobanking and Biomedical Research across Europe and Africa will dramatically improve and facilitate the development of better predictive, preventive and personalized healthcare worldwide. The rapidly evolving African biobanks are an invaluable resource: The African population has the greatest genomic diversity on the planet and represents an incredible resource of information ...
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12
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TERMINÉ
Design Principles of Microtubule Cytoskeleton Architectures during Cell Division (SPINDLEDESIGN)
Date du début: 1 juil. 2013, Date de fin: 30 juin 2018,
The microtubule cytoskeleton provides an intracellular coordinate system and a mechanical scaffold for a multitude of essential cellular functions. The design principles underlying the dynamic organisation and function of the microtubule cytoskeleton are not understood. Using an in vitro reconstitution approach, we will determine the rules that govern which combination of mechano-chemical elements ...
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2
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TERMINÉ
Vivre et travailler en Europe
Date du début: 1 juin 2016, Date de fin: 31 mai 2018,
Our goal is to provide students with additional foreign language skills in their professional field, but also open-mindedness and adaptability towards foreign countries in the perspective of living and working abroad.The 14 students concerned are in their junior year in a vocational high-school, and they will go abroad for 4 weeks (from May 29th to June 23th 2017).The teachers who are concerned a ...
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11
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TERMINÉ
Targeting RAS oncogene addiction (RASTARGET)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,
Lung cancer is the most common type of malignant tumour worldwide and the leading cause of cancer-related death (335,000 deaths per year in Europe). The KRAS oncogene is frequently activated by point mutation in human lung cancer and mutations in the RAS family oncogenes are responsible for driving some 20% of all human malignancies. Most cell lines from RAS mutant tumours remain “oncogene addicte ...
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2
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TERMINÉ
Standard method and online tool for assessing and improving the energy efficiency of wastewater treatment plants (ENERWATER)
Date du début: 1 mars 2015, Date de fin: 28 févr. 2018,
Waste Water Treatment Plants (WWTPs) is one of the most expensive public industries in terms of energy requirements accounting for more than 1% of consumption of electricity in Europe. EU Water Framework Directive (WFD) 91/271/CEE made obligatory waste water treatment for cities and towns. Now within the EU-27, the total number of WWTPs is estimated as 22.558, for which we can estimate a total ene ...
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10
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TERMINÉ
"Comparing policy framework, structure, effectiveness and cost-effectiveness of functional and integrated systems of mental health care" (COFI)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
"Mental disorders affect 38.2% of the EU population. For reducing the associated burden, countries across Europe engage in costly re-organizations of mental health care systems. Reforms focus on one controversial core question: Should systems be functional or integrated? In functional systems, separate staff in different services are in charge of in- and out-patient care (to enhance specialization ...
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7
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TERMINÉ
Metabolic functions of p53 in non-cancer pathologies (METABOp53)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2018,
... protein has resulted in a detailed understanding of its role in tumour suppression, information that is being used to develop small molecule modulators of p53 that are presently under evaluation for cancer therapy. However, it has recently become clear that p53 also plays roles in aspects of human health and disease extending beyond cancer - although most of these are poorly understood. We theref ...
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1
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TERMINÉ
ATMINistrating ATM signalling: exploring the significance of ATM regulation by ATMIN (ATMINDDR)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2018,
ATM is the protein kinase that is mutated in the hereditary autosomal recessive disease ataxia telangiectasia (A-T). A-T patients display immune deficiencies, cancer predisposition and radiosensitivity. The molecular role of ATM is to respond to DNA damage by phosphorylating its substrates, thereby promoting repair of damage or arresting the cell cycle. Following the induction of double-strand bre ...
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2
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TERMINÉ
European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,
ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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