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Articulating joint replacements represent a medical market exceeding €14 billion p.a. that is expected to rise as demographics reflect an ageing population. However, faster growth has been seen in the revision market, where prosthetic joints are replaced, than in primary interventions. The major cause of these revisions is that all joint replacements are prone to wear leading to loss of implant fu ...

Peri-implant disease is a true threat in today’s advancement of implant reliability and performance. The diagnostic approach followed in this grant is for early recognition of peri-implant diseases. Our System is sensing Matrix metalloproteinase 8 (MMP-8) regulation indicative for connective tissue degradation as present at the borderline of gingivitis/mucositis and periodontitis/peri-implantitis. ...