4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Fighting blindness of Usher syndrome: diagnosis, pathogenesis and retinal treatment (TreatRetUsher) (TREATRUSH)
Date du début: 1 févr. 2010, Date de fin: 31 janv. 2014,
Usher syndrome (USH) is the most frequent hereditary cause of deafness associated to blindness. It is a rare disease, affecting 1 in every 10.000 individuals, with an autosomal recessive monogenic inheritance. Deafness is congenital while the retinitis pigmentosa is not detected before the age of 8 to 10. These patients suffer from a dreadful disability as their two major senses are impaired. Impo ...
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13
Participants partenaires
TERMINÉ
Circuit specific approaches to retinal diseases (RETICIRC)
Date du début: 1 janv. 2009, Date de fin: 31 déc. 2011,
"The RETICIR project focuses on neuronal mechanisms of vision from photoreceptor level to visual cortex. Physiological knowledge of the visual system will be used to address pathophysiological neuronal mechanisms of diseases affecting vision. In the project we will identify molecular and cellular disease mechanism of retinitis pigmentosa and glaucoma, and will demonstrate restoration of vision in ...
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6
Participants partenaires
TERMINÉ
Functional Analysis of Genetically Identified Retinal Interneurons (Neural Circuits)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2010,
The classification of cell types that make up the brain has long been recognized as a prerequisites to understanding brain function. In addition, relating identified neurons to neural function has relied heavily on their inactivation. To answer such questions a tool that allows one to reliably target specific cells for recording, labeling and manipulation is needed. Here I describe a multidiscipli ...
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1
Participant partenaire
TERMINÉ
Imaging light evoked activity at different strata of the mammalian retina (RetActivityImaging)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2010,
"The mammalian visual system analyzes the world through a set of separate spatio-temporal channels. The organization of these channels begins in the retina where the precise laminations of both the axon terminals of bipolar cells and the dendritic arbors of ganglion cells form a vertical stack of neural strata at the inner plexiform layer. A major challenge is to understand how the different ""vis ...
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