5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
"Multimodular biomarker analysis workflow for diagnosis, prognosis and monitoring of drug treatment response in bladder cancer" (DIPROMON)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
"With the advent of Omics technologies capable of profiling substantial fractions of molecular entities from the genome down to the metabolome level a significant boost in understanding disease pathophysiology, consequently providing tailored diagnostics and therapy, was expected. With impressive results for selected diseases, cancer still sees significant shortcomings. One reason for this clinica ...
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6
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TERMINÉ
Markers for Sub-Clinical Cardiovascular Risk Assessemnt (EU-MASCARA)
Date du début: 1 déc. 2011, Date de fin: 31 mai 2016,
EU-MASCARA is a collaborative project that aims to improve diagnosis of cardiovascular diseases and prediction of cardiovascular risk by analysing a panel of biomarkers. EU-MASCARA aims to examine genetic, proteomic and metabolomic markers together with markers of inflammation, oxidative stress and cardiac remodelling to study their incremental diagnostic and predictive value over and above existi ...
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16
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TERMINÉ
Ovarian Cancer Therapy – Innovative Models Prolong Survival (OCTIPS)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
"About 75% of advanced epithelial ovarian cancer (EOC) patients respond to first-line surgery and chemotherapy but most relapse and ultimately acquire platinum resistance which soon leads to death. Relapsed high grade serous ovarian cancer (HGSOC) is the single main cause of EOC-related morbidity and mortality (despite the fact that HGSOC is highly chemosensitive). We hypothesize that the primary ...
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11
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TERMINÉ
Systems biology towards novel chronic kidney disease diagnosis and treatment (SysKID)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2014,
Chronic kidney disease (CKD) affects up to 10% of the population. Besides eventual progression towards end stage renal disease CKD impacts the patient’s quality of life by causing serious comorbidities including cardiovascular complications and bone metabolism disorders. On the everyday clinical level early stage diagnosis and tailored treatment of CKD are still inadequate. In addition, CKD seems ...
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30
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TERMINÉ
Profiling the toxicity of new drugs: a non animal-based approach integrating toxicodynamics and biokinetics (Predict-IV)
Date du début: 1 mai 2008, Date de fin: 31 oct. 2013,
The overall aim of Predict-IV is to develop strategies to improve the assessment of drug safety in the early stage of development and late discovery phase, by an intelligent combination of non animal-based test systems, cell biology, mechanistic toxicology and in-silico modelling, in a rapid and cost effective manner. A better prediction of the safety of an investigational compound in early develo ...
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